Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P

Updated on: February 23,2024

Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P

Updated on:February 23,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on: August 28,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on:August 28,2024

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer

by Denise Heady,University of California, Los AngelesGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101479A study by researchers at the UCLA Health

Updated on: March 30,2024

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer

by Denise Heady,University of California, Los AngelesGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101479A study by researchers at the UCLA Health

Updated on:March 30,2024

Exercise may help reduce long-term side effects of chemotherapy for breast cancer patients

by University of AmsterdamCredit: CC0 Public DomainAfter treatment for breast cancer, most women suffer side effects such as fatigue, not feeling physically fit and cognitive issues. This can oft

Updated on: February 24,2024

Exercise may help reduce long-term side effects of chemotherapy for breast cancer patients

by University of AmsterdamCredit: CC0 Public DomainAfter treatment for breast cancer, most women suffer side effects such as fatigue, not feeling physically fit and cognitive issues. This can oft

Updated on:February 24,2024

Survey finds one in three patients needed more information on cancer treatment side effects

by American Society for Radiation OncologyIn a nationwide survey of US adults treated for cancer, 1 in 3 patients said they experienced side effects from cancer treatment that they wish they'

Updated on: March 06,2024

Survey finds one in three patients needed more information on cancer treatment side effects

by American Society for Radiation OncologyIn a nationwide survey of US adults treated for cancer, 1 in 3 patients said they experienced side effects from cancer treatment that they wish they'

Updated on:March 06,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on: March 30,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on:March 30,2024

Breakthrough brings potential glioblastoma drug into focus

byKeck School of Medicine of USCA new type of small molecule drug, the first to target circadian clock proteins as a way to treat glioblastoma, is now in phase 1 clinical trials. Credit: Issey T

Updated on: January 07,2024

Breakthrough brings potential glioblastoma drug into focus

byKeck School of Medicine of USCA new type of small molecule drug, the first to target circadian clock proteins as a way to treat glioblastoma, is now in phase 1 clinical trials. Credit: Issey T

Updated on:January 07,2024

Stopping the resistance of cancer cells to treatment

by Colin Poitras,University of ConnecticutCredit: CC0 Public DomainOne of the drawbacks of chemotherapy is that cancer patients can build up resistance to treatment over time, increasing their c

Updated on: April 01,2024

Stopping the resistance of cancer cells to treatment

by Colin Poitras,University of ConnecticutCredit: CC0 Public DomainOne of the drawbacks of chemotherapy is that cancer patients can build up resistance to treatment over time, increasing their c

Updated on:April 01,2024

RNA-based therapy shows promise against aggressive childhood brain tumors in mice

by Johns Hopkins UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113938Targeting a non-encoding stretch of RNA may help shrink tumors caused by an aggressive type of b

Updated on: March 20,2024

RNA-based therapy shows promise against aggressive childhood brain tumors in mice

by Johns Hopkins UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113938Targeting a non-encoding stretch of RNA may help shrink tumors caused by an aggressive type of b

Updated on:March 20,2024

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on: June 01,2024

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on:June 01,2024

Vitamin A derivative selectively kills liver cancer stem cells

by RIKENRetinol or Vitamin A 3D space model (balls model). Credit: YassineMrabet, Wikipedia.Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurren

Updated on: March 06,2024

Vitamin A derivative selectively kills liver cancer stem cells

by RIKENRetinol or Vitamin A 3D space model (balls model). Credit: YassineMrabet, Wikipedia.Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurren

Updated on:March 06,2024

Pharmacoscopy improves therapy for relapsed blood cancer in a first clinical trial

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesPatient cells imaged by pharmacoscopy. Credit: CeMM/Gregory VladimerResearchers at CeMM and the Medical University of

Updated on: April 22,2024

Pharmacoscopy improves therapy for relapsed blood cancer in a first clinical trial

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesPatient cells imaged by pharmacoscopy. Credit: CeMM/Gregory VladimerResearchers at CeMM and the Medical University of

Updated on:April 22,2024