Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on: March 05,2024

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on:March 05,2024

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on: March 01,2024

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on:March 01,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on: February 18,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on:February 18,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on: June 24,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on:June 24,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on: June 28,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on:June 28,2024

Japan Nobel winner vows to continue research to 'save more patients than ever'

Credit: CC0 Public DomainThe Japanese scientist who Mondaywon the Nobel Prizefor medicine vowed to continue his cancer treatment work to help as many sufferers as possible, saying treating

Updated on: March 06,2024

Japan Nobel winner vows to continue research to 'save more patients than ever'

Credit: CC0 Public DomainThe Japanese scientist who Mondaywon the Nobel Prizefor medicine vowed to continue his cancer treatment work to help as many sufferers as possible, saying treating

Updated on:March 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on: June 24,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on:June 24,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on: March 30,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on:March 30,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024