New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on: November 08,2024

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on:November 08,2024

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

Updated on: December 01,2024

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

Updated on:December 01,2024

Improving CAR-T cell therapy for solid tumors through inhibition of conventional signaling pathway

byNational University of SingaporeGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100917Chimeric Antigen Receptor-expressing T cell (CAR-T) therapy i

Updated on: January 07,2024

Improving CAR-T cell therapy for solid tumors through inhibition of conventional signaling pathway

byNational University of SingaporeGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100917Chimeric Antigen Receptor-expressing T cell (CAR-T) therapy i

Updated on:January 07,2024

Cancer research explores role of cytochrome oxygenases in augmenting austocystin D-mediated cytotoxicity

byTokyo University of SciencePrevious studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. I

Updated on: September 06,2024

Cancer research explores role of cytochrome oxygenases in augmenting austocystin D-mediated cytotoxicity

byTokyo University of SciencePrevious studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. I

Updated on:September 06,2024

Modest rise in UK cancer cases but substantial decline in deaths over last 25 years: Study

by British Medical JournalCredit: Unsplash/CC0 Public DomainCases of cancer among UK men and women aged 35-69 years have seen a modest rise over the last quarter of a century, but there has also

Updated on: March 20,2024

Modest rise in UK cancer cases but substantial decline in deaths over last 25 years: Study

by British Medical JournalCredit: Unsplash/CC0 Public DomainCases of cancer among UK men and women aged 35-69 years have seen a modest rise over the last quarter of a century, but there has also

Updated on:March 20,2024

Cancer biology graduate student travels 'ROCKy' road toward a cure for post-radiation dry mouth

by University of ArizonaWen Yu "Amy" Wong. Credit: Gaius J. AugustusThe United States is in the midst of a head-and-neck cancer epidemic. Although survival rates are relatively high—aft

Updated on: March 12,2024

Cancer biology graduate student travels 'ROCKy' road toward a cure for post-radiation dry mouth

by University of ArizonaWen Yu "Amy" Wong. Credit: Gaius J. AugustusThe United States is in the midst of a head-and-neck cancer epidemic. Although survival rates are relatively high—aft

Updated on:March 12,2024

RNA nanoparticle therapy stops the spread of incurable bone marrow cancer, study finds

by Melissa Pappas, University of Pennsylvania School of Engineering and Applied ScienceCredit: Unsplash/CC0 Public DomainMultiple myeloma is an incurable bone marrow cancer that kills over 100,000 peo

Updated on: January 23,2024

RNA nanoparticle therapy stops the spread of incurable bone marrow cancer, study finds

by Melissa Pappas, University of Pennsylvania School of Engineering and Applied ScienceCredit: Unsplash/CC0 Public DomainMultiple myeloma is an incurable bone marrow cancer that kills over 100,000 peo

Updated on:January 23,2024

Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on: December 30,2023

Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on:December 30,2023

Two-pronged immunotherapy eliminates metastatic breast cancer in mice

by Julia Evangelou Strait,Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have identified a way to sensitize metastatic breast cancer

Updated on: January 04,2024

Two-pronged immunotherapy eliminates metastatic breast cancer in mice

by Julia Evangelou Strait,Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have identified a way to sensitize metastatic breast cancer

Updated on:January 04,2024

A partnership to tackle childhood cancers in developing countries

by St. Jude Children's Research HospitalCancer cell during cell division. Credit: National Institutes of HealthThe International Atomic Energy Agency (IAEA) and St. Jude Children's Resear

Updated on: April 23,2024

A partnership to tackle childhood cancers in developing countries

by St. Jude Children's Research HospitalCancer cell during cell division. Credit: National Institutes of HealthThe International Atomic Energy Agency (IAEA) and St. Jude Children's Resear

Updated on:April 23,2024

Breast cancer vaccine safely generates anti-tumor immunity

by Michael McCarthy.,University of WashingtonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI C

Updated on: January 03,2024

Breast cancer vaccine safely generates anti-tumor immunity

by Michael McCarthy.,University of WashingtonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI C

Updated on:January 03,2024

Trial shows promise for new antibody cancer treatment

byKing's College LondonMechanism of cytotoxicity mediated by MOv18 IgE. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-39679-9The first ever clinical trial of a new

Updated on: January 04,2024

Trial shows promise for new antibody cancer treatment

byKing's College LondonMechanism of cytotoxicity mediated by MOv18 IgE. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-39679-9The first ever clinical trial of a new

Updated on:January 04,2024