First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on: January 26,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on:January 26,2024

Lower prostate cancer screening rates associated with subsequent increase in advanced cancers

byAmerican Society for Radiation OncologyProstate cancer cells. Credit: NIH Image GalleryIn the face of conflicting evidence over the risks and benefits of routine prostate cancer screenings, a

Updated on: December 26,2023

Lower prostate cancer screening rates associated with subsequent increase in advanced cancers

byAmerican Society for Radiation OncologyProstate cancer cells. Credit: NIH Image GalleryIn the face of conflicting evidence over the risks and benefits of routine prostate cancer screenings, a

Updated on:December 26,2023

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on: March 06,2024

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on:March 06,2024

Oral sex is now the leading risk factor for throat cancer, says researcher

by Hisham Mehanna,The ConversationThe oropharynx is middle section of the throat (pharynx). Credit:Scientific Animations/Wikimedia Commons,CC BY-SAOver the past two decades, there ha

Updated on: January 30,2024

Oral sex is now the leading risk factor for throat cancer, says researcher

by Hisham Mehanna,The ConversationThe oropharynx is middle section of the throat (pharynx). Credit:Scientific Animations/Wikimedia Commons,CC BY-SAOver the past two decades, there ha

Updated on:January 30,2024

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on: January 07,2024

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on:January 07,2024

American Cancer Society issues nutrition, exercise guidelines for cancer survivors

In a guideline issued by the American Cancer Society and published in the May/June issue ofCA: A Cancer Journal for Clinicians, recommendations are presented regarding diet and exercise for redu

Updated on: December 28,2023

American Cancer Society issues nutrition, exercise guidelines for cancer survivors

In a guideline issued by the American Cancer Society and published in the May/June issue ofCA: A Cancer Journal for Clinicians, recommendations are presented regarding diet and exercise for redu

Updated on:December 28,2023

How sweet it isn't: Diminished taste function affects cancer patients' food intake

by Alissa Nolden,University of Massachusetts AmherstAlissa Nolden is an assistant professor of food science at UMass Amherst. Credit: UMass AmherstThe simple pleasure of tasting and savoring foo

Updated on: May 09,2024

How sweet it isn't: Diminished taste function affects cancer patients' food intake

by Alissa Nolden,University of Massachusetts AmherstAlissa Nolden is an assistant professor of food science at UMass Amherst. Credit: UMass AmherstThe simple pleasure of tasting and savoring foo

Updated on:May 09,2024

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on: December 18,2023

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on:December 18,2023

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on: May 07,2024

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on:May 07,2024

Researchers find new way to target childhood cancer

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainAn Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the child

Updated on: June 01,2024

Researchers find new way to target childhood cancer

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainAn Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the child

Updated on:June 01,2024

Inside the new colorectal cancer screening guidelines for average-risk patients

by Mayo Clinic News NetworkCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The American College of Physicians has produced a guidance statement for colorectal cancer s

Updated on: April 20,2024

Inside the new colorectal cancer screening guidelines for average-risk patients

by Mayo Clinic News NetworkCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The American College of Physicians has produced a guidance statement for colorectal cancer s

Updated on:April 20,2024

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on: December 28,2023

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on:December 28,2023