'Masked' cancer drug sneaks through body to deliver anti-tumor treatment with fewer side effects

by University of ChicagoCredit: CC0 Public DomainMany cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side e

Updated on: March 30,2024

'Masked' cancer drug sneaks through body to deliver anti-tumor treatment with fewer side effects

by University of ChicagoCredit: CC0 Public DomainMany cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side e

Updated on:March 30,2024

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on: February 20,2024

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on:February 20,2024

Researchers develop priorities for interventions to address health disparities in lung nodule management

by Boston University School of MedicineCascade-of-care framework for identifying potential areas for intervention to reduce disparities in lung nodule evaluation. This figure shows each step of a

Updated on: February 20,2024

Researchers develop priorities for interventions to address health disparities in lung nodule management

by Boston University School of MedicineCascade-of-care framework for identifying potential areas for intervention to reduce disparities in lung nodule evaluation. This figure shows each step of a

Updated on:February 20,2024

Harms reporting is inconsistent across organ cancer guidelines

byAmerican College of PhysiciansCredit: CC0 Public DomainA review of 33 organ-specific cancer screening guidelines has found that the reporting of harms related to screening tests and procedures

Updated on: December 22,2023

Harms reporting is inconsistent across organ cancer guidelines

byAmerican College of PhysiciansCredit: CC0 Public DomainA review of 33 organ-specific cancer screening guidelines has found that the reporting of harms related to screening tests and procedures

Updated on:December 22,2023

Regular exercise should be part of cancer care for all patients

byEuropean Society for Medical OncologyQuality of life scores before and after chemotherapy in active and inactive patients. Credit: European Society for Medical OncologyIncluding exercise or sp

Updated on: December 18,2023

Regular exercise should be part of cancer care for all patients

byEuropean Society for Medical OncologyQuality of life scores before and after chemotherapy in active and inactive patients. Credit: European Society for Medical OncologyIncluding exercise or sp

Updated on:December 18,2023

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on: March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on:March 27,2024

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on: January 04,2024

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on:January 04,2024

Anti-PF4 Immunothrombosis Absent Proximate Heparin or Adenovirus Vector Vaccine Exposure

February 2024Lara C. Pullen, PhDNew research reveals that patients with thrombocytopenia, thrombosis, and very high D-dimer levels could have platelet-activating vaccine-induced immune thrombocytopeni

Updated on: February 18,2024

Anti-PF4 Immunothrombosis Absent Proximate Heparin or Adenovirus Vector Vaccine Exposure

February 2024Lara C. Pullen, PhDNew research reveals that patients with thrombocytopenia, thrombosis, and very high D-dimer levels could have platelet-activating vaccine-induced immune thrombocytopeni

Updated on:February 18,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on: March 25,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on:March 25,2024

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on: December 25,2023

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on:December 25,2023

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on: December 22,2023

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on:December 22,2023

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li

Updated on: April 02,2024

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li

Updated on:April 02,2024