Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib

byThe Spanish National Cancer Research CentreSotorasib-resistant lung cancer cells displaying multiple copies of the mutated KRAS gene (in red) / CICANCER. Credit: CICANCERAccording to recent fi

Updated on: December 27,2023

Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib

byThe Spanish National Cancer Research CentreSotorasib-resistant lung cancer cells displaying multiple copies of the mutated KRAS gene (in red) / CICANCER. Credit: CICANCERAccording to recent fi

Updated on:December 27,2023

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on: December 18,2023

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on:December 18,2023

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on: December 18,2023

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on:December 18,2023

Study reveals why testicular cancer is so responsive to chemo

by Cornell UniversityA low magnification image of a germ cell tumor, called a teratocarcinoma, from a new mouse model developed to study testicular cancer. A cluster of cancer stem cells, termed

Updated on: July 02,2024

Study reveals why testicular cancer is so responsive to chemo

by Cornell UniversityA low magnification image of a germ cell tumor, called a teratocarcinoma, from a new mouse model developed to study testicular cancer. A cluster of cancer stem cells, termed

Updated on:July 02,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on: July 17,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on:July 17,2024

Activated vitamin D3 treatment may reduce the risk of arsenic-mediated skin cancer

by Shibaura Institute of TechnologyThe risk of cancer associated with long-term exposure to arsenic in drinking water can be mitigated through regular treatment with calcitriol, an activated form of v

Updated on: December 25,2023

Activated vitamin D3 treatment may reduce the risk of arsenic-mediated skin cancer

by Shibaura Institute of TechnologyThe risk of cancer associated with long-term exposure to arsenic in drinking water can be mitigated through regular treatment with calcitriol, an activated form of v

Updated on:December 25,2023

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on: January 02,2024

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on:January 02,2024

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on: August 27,2024

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on:August 27,2024

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on: April 14,2024

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on:April 14,2024

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on: December 20,2023

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on:December 20,2023

Measuring tumor infiltrating lymphocytes predicts long term outcomes for type of early breast cancer

byQueen Mary, University of LondonBenefit of radiotherapy in preventing IBE by CPath TIL categories. Credit:The Lancet Digital Health(2024). DOI: 10.1016/S2589-7500(24)00116-XResearc

Updated on: July 11,2024

Measuring tumor infiltrating lymphocytes predicts long term outcomes for type of early breast cancer

byQueen Mary, University of LondonBenefit of radiotherapy in preventing IBE by CPath TIL categories. Credit:The Lancet Digital Health(2024). DOI: 10.1016/S2589-7500(24)00116-XResearc

Updated on:July 11,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024