IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on: October 10,2023

IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on:October 10,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on: October 11,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on:October 11,2023

New insight into BRCA2 gene mutations and cancer risk

A recent study from researchers at the University of California examines the BRCA2 gene, which plays a crucial role in repairing damaged DNA, and possible links with increased risk of breast and ovari

Updated on: October 31,2023

New insight into BRCA2 gene mutations and cancer risk

A recent study from researchers at the University of California examines the BRCA2 gene, which plays a crucial role in repairing damaged DNA, and possible links with increased risk of breast and ovari

Updated on:October 31,2023

Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig

Updated on: October 31,2023

Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig

Updated on:October 31,2023

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on: January 08,2024

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on:January 08,2024

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on: October 11,2023

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on:October 11,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MD Prithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal t

Updated on: October 10,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MD Prithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal t

Updated on:October 10,2023

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on: January 08,2024

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on:January 08,2024

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on: January 08,2024

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on:January 08,2024

Immunotherapy for Cancer: What Are My Options?

ByJennifer WelshPublished on September 06, 2023Medically reviewed byDoru Paul, MDImmunotherapy is a relatively new approach to cancer treatment. It improves the body's immu

Updated on: November 20,2023

Immunotherapy for Cancer: What Are My Options?

ByJennifer WelshPublished on September 06, 2023Medically reviewed byDoru Paul, MDImmunotherapy is a relatively new approach to cancer treatment. It improves the body's immu

Updated on:November 20,2023

Single set of criteria to assess progression in glioma aims to speed discovery of new medicines

byDana-Farber Cancer InstituteInfant high-grade glioma. Credit: David Ellison, St. Jude Children’s Research HospitalIn order to accurately assess the efficacy of novel therapies for brain tumors

Updated on: October 31,2023

Single set of criteria to assess progression in glioma aims to speed discovery of new medicines

byDana-Farber Cancer InstituteInfant high-grade glioma. Credit: David Ellison, St. Jude Children’s Research HospitalIn order to accurately assess the efficacy of novel therapies for brain tumors

Updated on:October 31,2023

Novel risk score for cardiovascular complications after bone marrow transplant

by Noah Fromson,University of Michigan3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHFor thousands of Americans each year, a bone marrow transplant has the potential to cure diseases s

Updated on: March 20,2024

Novel risk score for cardiovascular complications after bone marrow transplant

by Noah Fromson,University of Michigan3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHFor thousands of Americans each year, a bone marrow transplant has the potential to cure diseases s

Updated on:March 20,2024