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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Early genome catastrophes can cause non-smoking lung cancer

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI
Existing cancer drugs have potential to benefit thousands more patients, research shows

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1
Continuity of care needed from the 'front of the pathway' to the back for cancer survivors, reports study

Continuity of care needed from the 'front of the pathway' to the back for cancer survivors, reports study

byUniversity of OtagoCredit: Pixabay/CC0 Public DomainAfter undergoing cancer treatment, many survivors deal with a range of psycho-social and physical issues but support for them is limited, ne

Continuity of care needed from the 'front of the pathway' to the back for cancer survivors, reports study

byUniversity of OtagoCredit: Pixabay/CC0 Public DomainAfter undergoing cancer treatment, many survivors deal with a range of psycho-social and physical issues but support for them is limited, ne
Stopping the spread: Targeting tumor metastasis

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep
Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t
A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno
Technique targets cancer cells and leaves healthy ones alone

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo
Study reveals pathways for aggressive prostate cancer subtype

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati
Aerobic exercise cuts chemotherapy-induced peripheral neuropathy symptoms

Aerobic exercise cuts chemotherapy-induced peripheral neuropathy symptoms

by Lori SolomonA six-month aerobic exercise intervention significantly improves self-reported chemotherapy-induced peripheral neuropathy (CIPN) among patients treated for ovarian cancer, according to

Aerobic exercise cuts chemotherapy-induced peripheral neuropathy symptoms

by Lori SolomonA six-month aerobic exercise intervention significantly improves self-reported chemotherapy-induced peripheral neuropathy (CIPN) among patients treated for ovarian cancer, according to
Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel

Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel

by Julia Evangelou Strait,Washington University in St. LouisThin slice of a human prostate tumor. The dark staining throughout reveals the presence of histone acetylation promoting cholesterol p

Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel

by Julia Evangelou Strait,Washington University in St. LouisThin slice of a human prostate tumor. The dark staining throughout reveals the presence of histone acetylation promoting cholesterol p
Reprogramming of immune cells shown to fight off melanoma

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o
Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu