New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on: January 12,2024 12

New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on:January 12,2024 12

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on: March 12,2024 17

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on:March 12,2024 17

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on: March 30,2024 0

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on:March 30,2024 0

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on: February 18,2024 17

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on:February 18,2024 17

Diverticular disease associated with cancer outside gastrointestinal tract

by Karolinska InstitutetIllustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of HealthThrough the ESPRESSO cohort, researc

Updated on: February 18,2024 12

Diverticular disease associated with cancer outside gastrointestinal tract

by Karolinska InstitutetIllustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of HealthThrough the ESPRESSO cohort, researc

Updated on:February 18,2024 12

Study finds that trust in cancer information declined among Black Americans during the pandemic

byTaylor & FrancisCredit: Unsplash/CC0 Public DomainTrust in information given out by the government on cancer fell sharply among the Black population—by almost half—during the COVID-19 pand

Updated on: January 23,2024 18

Study finds that trust in cancer information declined among Black Americans during the pandemic

byTaylor & FrancisCredit: Unsplash/CC0 Public DomainTrust in information given out by the government on cancer fell sharply among the Black population—by almost half—during the COVID-19 pand

Updated on:January 23,2024 18

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024 4

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024 4

Researchers link overexpression of MDMX protein to metastasis of 3X negative breast cancer

by The City University of New YorkThe MDMX and MDM2 proteins promote metastasis in triple-negative breast cancer, while the MDM2 protein promotes tumor growth in estrogen receptor a-positive brea

Updated on: June 15,2024 7

Researchers link overexpression of MDMX protein to metastasis of 3X negative breast cancer

by The City University of New YorkThe MDMX and MDM2 proteins promote metastasis in triple-negative breast cancer, while the MDM2 protein promotes tumor growth in estrogen receptor a-positive brea

Updated on:June 15,2024 7

Only a third of women take up all offered cancer screenings, new research finds

by King's College LondonCredit: CC0 Public DomainIn a paper published today in theJournal of Medical Screening, researchers from King's College London and Queen Mary University of L

Updated on: March 09,2024 13

Only a third of women take up all offered cancer screenings, new research finds

by King's College LondonCredit: CC0 Public DomainIn a paper published today in theJournal of Medical Screening, researchers from King's College London and Queen Mary University of L

Updated on:March 09,2024 13

Researchers develop comprehensive new way to predict breast cancer risk

by Cancer Research UKThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli,

Updated on: June 08,2024 3

Researchers develop comprehensive new way to predict breast cancer risk

by Cancer Research UKThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli,

Updated on:June 08,2024 3

Crucial role of JUN protein in restraining liver cancer growth discovered

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Synopsis. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-024-00188-0A team of scientists led by Dr. Björn von Eyss has disc

Updated on: September 07,2024 0

Crucial role of JUN protein in restraining liver cancer growth discovered

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Synopsis. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-024-00188-0A team of scientists led by Dr. Björn von Eyss has disc

Updated on:September 07,2024 0

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on: March 01,2024 13

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on:March 01,2024 13