Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on: February 23,2024

Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on:February 23,2024

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on: January 30,2024

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on:January 30,2024

Differences found in how doctors, caregivers and patients report side effects of cancer therapy

by Children's Hospital Los AngelesCredit: CC0 Public DomainA recent study reveals differences in how symptom toxicity is reported for children receiving cancer treatment in clinical trials. D

Updated on: February 03,2024

Differences found in how doctors, caregivers and patients report side effects of cancer therapy

by Children's Hospital Los AngelesCredit: CC0 Public DomainA recent study reveals differences in how symptom toxicity is reported for children receiving cancer treatment in clinical trials. D

Updated on:February 03,2024

Crossroads: The role of biomarkers in the management of lumps in the breast

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new research perspective was published inOncotarget's, titled "Crossroads: the role of biomarkers in the management of lumps in

Updated on: January 04,2024

Crossroads: The role of biomarkers in the management of lumps in the breast

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new research perspective was published inOncotarget's, titled "Crossroads: the role of biomarkers in the management of lumps in

Updated on:January 04,2024

Self-reported screening can reduce distressing symptoms for pediatric patients with cancer

byUniversity of TorontoCredit: Unsplash/CC0 Public DomainRegular, self-reported symptom screening was associated with reduced symptom burden when compared with usual care for pediatric patients

Updated on: December 01,2024

Self-reported screening can reduce distressing symptoms for pediatric patients with cancer

byUniversity of TorontoCredit: Unsplash/CC0 Public DomainRegular, self-reported symptom screening was associated with reduced symptom burden when compared with usual care for pediatric patients

Updated on:December 01,2024

Study identifies five key factors that predict response of cancer patients to immunotherapy

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patien

Updated on: September 28,2024

Study identifies five key factors that predict response of cancer patients to immunotherapy

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patien

Updated on:September 28,2024

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on: February 03,2024

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on:February 03,2024

Two-stage transplantation is a viable treatment option for liver metastases, shows study

by Uta von der Gönna, Universitätsklinikum JenaSurgical procedure: At first, only a lobe of the liver with metastases (1) is removed (2) and replaced with a healthy partial organ. Reduced blood flow t

Updated on: January 16,2024

Two-stage transplantation is a viable treatment option for liver metastases, shows study

by Uta von der Gönna, Universitätsklinikum JenaSurgical procedure: At first, only a lobe of the liver with metastases (1) is removed (2) and replaced with a healthy partial organ. Reduced blood flow t

Updated on:January 16,2024

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on: January 22,2024

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on:January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on: January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on:January 22,2024

Study uncovers genetic cancer risks in 550 patients

by Susan Murphy,Mayo ClinicCredit: CC0 Public DomainCurrent screening protocols fail to catch a notable number of people carrying genetic mutations associated with hereditary breast and ovarian

Updated on: August 01,2024

Study uncovers genetic cancer risks in 550 patients

by Susan Murphy,Mayo ClinicCredit: CC0 Public DomainCurrent screening protocols fail to catch a notable number of people carrying genetic mutations associated with hereditary breast and ovarian

Updated on:August 01,2024

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on: January 22,2024

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on:January 22,2024