Minimal residual disease negativity predicts time to next treatment in multiple myeloma

by Elana GotkineFor patients with multiple myeloma (MM), minimal residual disease (MRD) negativity determined using next-generation sequencing (NGS) is predictive of longer time to next treatment (TTN

Updated on: January 22,2024

Minimal residual disease negativity predicts time to next treatment in multiple myeloma

by Elana GotkineFor patients with multiple myeloma (MM), minimal residual disease (MRD) negativity determined using next-generation sequencing (NGS) is predictive of longer time to next treatment (TTN

Updated on:January 22,2024

Researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice

by Stanford University Medical CenterCredit: CC0 Public DomainA new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiven

Updated on: June 24,2024

Researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice

by Stanford University Medical CenterCredit: CC0 Public DomainA new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiven

Updated on:June 24,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

New treatments, screening methods dramatically reduce breast cancer deaths, study finds

by Stanford University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainIn the last few decades, dozens of new breast cancer drugs—fr

Updated on: March 01,2024

New treatments, screening methods dramatically reduce breast cancer deaths, study finds

by Stanford University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainIn the last few decades, dozens of new breast cancer drugs—fr

Updated on:March 01,2024

Study outlines need for measures that improve information and autonomy for cancer patients

by University of BergenStudy design. This paper is about sub-study 4. Credit:Lung Cancer(2023). DOI: 10.1016/j.lungcan.2023.107312A new study shows that patients can experience reduce

Updated on: February 01,2024

Study outlines need for measures that improve information and autonomy for cancer patients

by University of BergenStudy design. This paper is about sub-study 4. Credit:Lung Cancer(2023). DOI: 10.1016/j.lungcan.2023.107312A new study shows that patients can experience reduce

Updated on:February 01,2024

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on: January 04,2024

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on:January 04,2024

Germline testing underused in cancer patients

by Lori SolomonFew patients diagnosed with cancer between 2013 and 2019 in California and Georgia underwent germline testing, according to a study published online June 5 in theJournal of the Am

Updated on: January 04,2024

Germline testing underused in cancer patients

by Lori SolomonFew patients diagnosed with cancer between 2013 and 2019 in California and Georgia underwent germline testing, according to a study published online June 5 in theJournal of the Am

Updated on:January 04,2024

Allogenic hematopoietic cell transplant a viable option for high-risk myelodysplastic syndrome, study suggests

byDana-Farber Cancer InstituteClinical outcomes by TP53 allelic state. (A) OS by TP53 allelic state. (B) Cumulative incidence of MDS relapse or progression to AML by TP53 allelic state, with dea

Updated on: January 16,2024

Allogenic hematopoietic cell transplant a viable option for high-risk myelodysplastic syndrome, study suggests

byDana-Farber Cancer InstituteClinical outcomes by TP53 allelic state. (A) OS by TP53 allelic state. (B) Cumulative incidence of MDS relapse or progression to AML by TP53 allelic state, with dea

Updated on:January 16,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on: November 10,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on:November 10,2024

Syrian refugees are diagnosed with breast cancer younger and with more advanced tumors, study finds

byBrigham and Women’s HospitalCredit: Unsplash/CC0 Public DomainBrigham researchers and international collaborators identified the association with younger age and advanced stage at diagnosis, c

Updated on: January 23,2024

Syrian refugees are diagnosed with breast cancer younger and with more advanced tumors, study finds

byBrigham and Women’s HospitalCredit: Unsplash/CC0 Public DomainBrigham researchers and international collaborators identified the association with younger age and advanced stage at diagnosis, c

Updated on:January 23,2024

In high-risk neuroblastoma, two stem cell transplants may be better than one

by Nancy Fliesler,Children's Hospital BostonCredit: Children's Hospital BostonSince the early 1990s, chemotherapy followed by an autologous stem cell transplant has been the standard of

Updated on: March 09,2024

In high-risk neuroblastoma, two stem cell transplants may be better than one

by Nancy Fliesler,Children's Hospital BostonCredit: Children's Hospital BostonSince the early 1990s, chemotherapy followed by an autologous stem cell transplant has been the standard of

Updated on:March 09,2024

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on: January 11,2024

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on:January 11,2024