Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on: April 18,2024

Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on:April 18,2024

Cancer in Europe: more cases but fewer deaths

Credit: CC0 Public DomainThe number of cancer cases has continued to rise across Europe, however mortality rates from the disease have fallen, according to the World Health Organization's "Eu

Updated on: March 06,2024

Cancer in Europe: more cases but fewer deaths

Credit: CC0 Public DomainThe number of cancer cases has continued to rise across Europe, however mortality rates from the disease have fallen, according to the World Health Organization's "Eu

Updated on:March 06,2024

Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel

by Julia Evangelou Strait,Washington University in St. LouisThin slice of a human prostate tumor. The dark staining throughout reveals the presence of histone acetylation promoting cholesterol p

Updated on: February 23,2024

Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel

by Julia Evangelou Strait,Washington University in St. LouisThin slice of a human prostate tumor. The dark staining throughout reveals the presence of histone acetylation promoting cholesterol p

Updated on:February 23,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

Long-term collection of patient-reported outcome data in oncology trials: Important and feasible

by Institute for Quality and Efficiency in Health CareCredit: CC0 Public DomainPatient-reported outcome (PRO) data are collected in oncology trials to determine patients' perspectives of canc

Updated on: January 30,2024

Long-term collection of patient-reported outcome data in oncology trials: Important and feasible

by Institute for Quality and Efficiency in Health CareCredit: CC0 Public DomainPatient-reported outcome (PRO) data are collected in oncology trials to determine patients' perspectives of canc

Updated on:January 30,2024

Fake organs guide the way for 'impossible' cancer surgery

by Mark Michaud,University of Rochester Medical CenterAhmed Ghazi, M.D., holds a lifelike model of Anthony Camnetar's kidney. Credit: University of Rochester Medical CenterAnthony Camnetar r

Updated on: March 06,2024

Fake organs guide the way for 'impossible' cancer surgery

by Mark Michaud,University of Rochester Medical CenterAhmed Ghazi, M.D., holds a lifelike model of Anthony Camnetar's kidney. Credit: University of Rochester Medical CenterAnthony Camnetar r

Updated on:March 06,2024

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D

Updated on: January 04,2024

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D

Updated on:January 04,2024

New research: Immune cells that fight cancer become exhausted within hours of first encountering tumors

by Mary Philip and Michael Rudloff,The ConversationThis microscopy image shows a cytotoxic T cell (blue) attacking a cancer cell (green) by releasing toxic chemicals (red). Credit:Alex Rit

Updated on: January 12,2024

New research: Immune cells that fight cancer become exhausted within hours of first encountering tumors

by Mary Philip and Michael Rudloff,The ConversationThis microscopy image shows a cytotoxic T cell (blue) attacking a cancer cell (green) by releasing toxic chemicals (red). Credit:Alex Rit

Updated on:January 12,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on: February 18,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on:February 18,2024

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on: February 01,2024

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on:February 01,2024

Study: AI outperforms standard risk model for predicting breast cancer

by Radiological Society of North AmericaRight medial lateral oblique (RMLO) screening mammograms show negative results from 2016 in (A) a 73-year-old woman with Mirai artificial intelligence (AI)

Updated on: February 03,2024

Study: AI outperforms standard risk model for predicting breast cancer

by Radiological Society of North AmericaRight medial lateral oblique (RMLO) screening mammograms show negative results from 2016 in (A) a 73-year-old woman with Mirai artificial intelligence (AI)

Updated on:February 03,2024