Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on: January 22,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on:January 22,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on: April 28,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on:April 28,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on: February 24,2024

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on:February 24,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on: January 30,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on:January 30,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on: February 18,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on:February 18,2024

Prevalence of routine breast cancer screening practices among migrant-Australian women

by University of Western SydneyCredit: University of Western SydneyDespite increased awareness of the prevalence of breast cancer and importance of early detection, a Western Sydney University st

Updated on: March 08,2024

Prevalence of routine breast cancer screening practices among migrant-Australian women

by University of Western SydneyCredit: University of Western SydneyDespite increased awareness of the prevalence of breast cancer and importance of early detection, a Western Sydney University st

Updated on:March 08,2024

Researchers develop novel approach for predicting resistance against cancer therapy

by National University of SingaporeMultispectral microscopy with quantitative immunofluorescence is a state-of-the-art technology that can detect oncogenes simultaneously, allowing for the identi

Updated on: February 18,2024

Researchers develop novel approach for predicting resistance against cancer therapy

by National University of SingaporeMultispectral microscopy with quantitative immunofluorescence is a state-of-the-art technology that can detect oncogenes simultaneously, allowing for the identi

Updated on:February 18,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024

Researchers identify immune cell that helps kill bladder cancer tumors

by The Mount Sinai HospitalMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteMount Sinai researchers have made two imp

Updated on: February 18,2024

Researchers identify immune cell that helps kill bladder cancer tumors

by The Mount Sinai HospitalMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteMount Sinai researchers have made two imp

Updated on:February 18,2024