Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi

Updated on: March 01,2024

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi

Updated on:March 01,2024

Researchers identify genetic 'seeds' of metastatic breast cancer

by UNC Lineberger Comprehensive Cancer CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast cancer is the second leading cause of cancer d

Updated on: March 01,2024

Researchers identify genetic 'seeds' of metastatic breast cancer

by UNC Lineberger Comprehensive Cancer CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast cancer is the second leading cause of cancer d

Updated on:March 01,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on: March 30,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on:March 30,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on: February 18,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on:February 18,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on: January 12,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on:January 12,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance

Updated on: June 04,2024

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance

Updated on:June 04,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on: June 24,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on:June 24,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024