Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on: December 22,2023

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on:December 22,2023

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend

Updated on: March 15,2024

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend

Updated on:March 15,2024

Blood-clotting protein and blood platelets promote immune evasion, cancer progression

byOhio State University Medical CenterCredit: CC0 Public DomainA new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard

Updated on: December 20,2023

Blood-clotting protein and blood platelets promote immune evasion, cancer progression

byOhio State University Medical CenterCredit: CC0 Public DomainA new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard

Updated on:December 20,2023

Cancers engaged in evolutionary arms race with immune system

byInstitute of Cancer ResearchMultiplex immunohistochemistry image of T-cells infiltrating stomach tumours. Credit: Katharina von Loga, Biomedical Research CentreAggressive, highly mutated cance

Updated on: December 22,2023

Cancers engaged in evolutionary arms race with immune system

byInstitute of Cancer ResearchMultiplex immunohistochemistry image of T-cells infiltrating stomach tumours. Credit: Katharina von Loga, Biomedical Research CentreAggressive, highly mutated cance

Updated on:December 22,2023

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on: March 14,2024

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on:March 14,2024

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on: December 22,2023

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on:December 22,2023

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on: February 18,2024

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on:February 18,2024

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on: December 22,2023

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on:December 22,2023

Research supports TCM liver-breast cancer theory: Fatty liver linked to deteriorating breast cancer

byThe University of Hong KongA) Trial schematic for establishing an HFD-fed NAFLD-breast cancer mice model. B, C) Mice on the HFD diet showed accelerated body weight growth (B) and higher body f

Updated on: July 11,2024

Research supports TCM liver-breast cancer theory: Fatty liver linked to deteriorating breast cancer

byThe University of Hong KongA) Trial schematic for establishing an HFD-fed NAFLD-breast cancer mice model. B, C) Mice on the HFD diet showed accelerated body weight growth (B) and higher body f

Updated on:July 11,2024

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on: December 22,2023

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on:December 22,2023