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Hematology&Oncology
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Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

byCity of Hope National Medical CenterStructure showing the targetable sites of the City of Hope-discovered YTHDF2 protein. Credit: Dr. Jianjun Chen's Lab / City of HopeScientists at City of

Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

byCity of Hope National Medical CenterStructure showing the targetable sites of the City of Hope-discovered YTHDF2 protein. Credit: Dr. Jianjun Chen's Lab / City of HopeScientists at City of
Imaging technique allows rapid assessment of ovarian cancer subtypes and their response to treatment

Imaging technique allows rapid assessment of ovarian cancer subtypes and their response to treatment

byUniversity of CambridgeThese images, from a small-scale unpublished study in human ovarian cancer patients, were created using a technique called hyperpolarized carbon-13 imaging that allows d

Imaging technique allows rapid assessment of ovarian cancer subtypes and their response to treatment

byUniversity of CambridgeThese images, from a small-scale unpublished study in human ovarian cancer patients, were created using a technique called hyperpolarized carbon-13 imaging that allows d
Molecular 'ZIP code' draws killer T cells to brain tumors

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s
Microscopic cell changes linked to cancer's rapid growth in stiff tissues

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,
Proof-of-concept study bioengineers therapeutics for improved cancer treatment

Proof-of-concept study bioengineers therapeutics for improved cancer treatment

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainA team of Children's Medical Research Institute (CMRI) scientists has identified a new method for producing a therapeut

Proof-of-concept study bioengineers therapeutics for improved cancer treatment

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainA team of Children's Medical Research Institute (CMRI) scientists has identified a new method for producing a therapeut
Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP
New treatment target for neuroendocrine prostate cancer discovered

New treatment target for neuroendocrine prostate cancer discovered

by Roswell Park Comprehensive Cancer CenterMitochondria are dysfunctional in neuroendocrine prostate tumors. Credit:Oncogene(2024). DOI: 10.1038/s41388-024-03261-4A team of researchers at

New treatment target for neuroendocrine prostate cancer discovered

by Roswell Park Comprehensive Cancer CenterMitochondria are dysfunctional in neuroendocrine prostate tumors. Credit:Oncogene(2024). DOI: 10.1038/s41388-024-03261-4A team of researchers at
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Changes in blood cell production over the lifetime could impact leukemia outcomes

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop
Overcoming glioblastoma resistance to chemotherapy

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &