Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n

Updated on: April 28,2024 0

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n

Updated on:April 28,2024 0

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Updated on: April 28,2024 0

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Updated on:April 28,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on: April 28,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on:April 28,2024 0

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Updated on: April 28,2024 0

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Updated on:April 28,2024 0

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic

Updated on: April 28,2024 0

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic

Updated on:April 28,2024 0

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Updated on: April 28,2024 0

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Updated on:April 28,2024 0

Researchers compile detailed catalog of bacteria living in cancer metastases

byNetherlands Cancer InstituteCredit: CC0 Public DomainResearchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases. Having analyzed o

Updated on: April 28,2024 0

Researchers compile detailed catalog of bacteria living in cancer metastases

byNetherlands Cancer InstituteCredit: CC0 Public DomainResearchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases. Having analyzed o

Updated on:April 28,2024 0

New potential avenues for cancer therapies through RNA-binding proteins

byKing's College LondonGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109288A new paper describes the role of two RNA-binding proteins in the development of

Updated on: April 28,2024 0

New potential avenues for cancer therapies through RNA-binding proteins

byKing's College LondonGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109288A new paper describes the role of two RNA-binding proteins in the development of

Updated on:April 28,2024 0

Blood stem cells unlock clues for helping sepsis patients fight recurring infections

Blood stem cells unlock clues for helping sepsis patients fight recurring infectionsby International Society for Stem Cell ResearchCredit: Pixabay/CC0 Public DomainSevere sepsis from bacterial or vira

Updated on: April 28,2024 0

Blood stem cells unlock clues for helping sepsis patients fight recurring infections

Blood stem cells unlock clues for helping sepsis patients fight recurring infectionsby International Society for Stem Cell ResearchCredit: Pixabay/CC0 Public DomainSevere sepsis from bacterial or vira

Updated on:April 28,2024 0

Study of data from thousands of women suggests ovarian cycle is regulated by circadian rhythm

by Bob Yirka , Medical XpressCredit: Puwadon Sang-ngern from PexelsA team of reproductive researchers affiliated with several institutions in France and the U.S. has found that the timing of monthly o

Updated on: April 28,2024 0

Study of data from thousands of women suggests ovarian cycle is regulated by circadian rhythm

by Bob Yirka , Medical XpressCredit: Puwadon Sang-ngern from PexelsA team of reproductive researchers affiliated with several institutions in France and the U.S. has found that the timing of monthly o

Updated on:April 28,2024 0

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on: April 28,2024 0

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on:April 28,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on: April 28,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on:April 28,2024 0