Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Updated on: April 24,2024 15

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Updated on:April 24,2024 15

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V

Updated on: April 23,2024 17

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V

Updated on:April 23,2024 17

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on: April 23,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on:April 23,2024 0

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on: April 23,2024 0

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on:April 23,2024 0

Endothelial AHR Signaling: A Key Regulator of Immune Defense

Updated on: April 20,2024 0

Endothelial AHR Signaling: A Key Regulator of Immune Defense

Updated on:April 20,2024 0

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther

Updated on: April 18,2024 0

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther

Updated on:April 18,2024 0

JAMA report outlines recommendations for evaluation and management of penicillin allergy

by Massachusetts General HospitalCredit: CC0 Public DomainWhile more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that

Updated on: April 16,2024 20

JAMA report outlines recommendations for evaluation and management of penicillin allergy

by Massachusetts General HospitalCredit: CC0 Public DomainWhile more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that

Updated on:April 16,2024 20

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on: April 12,2024 20

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on:April 12,2024 20

CRISPR treatment slows swelling in hereditary angioedema patients

by American College of Allergy, Asthma, and ImmunologyCredit: James atmos, CC BY-SA 3.0, via Wikimedia CommonsHereditary angioedema (HAE) is a rare, genetic disorder characterized by severe

Updated on: April 12,2024 19

CRISPR treatment slows swelling in hereditary angioedema patients

by American College of Allergy, Asthma, and ImmunologyCredit: James atmos, CC BY-SA 3.0, via Wikimedia CommonsHereditary angioedema (HAE) is a rare, genetic disorder characterized by severe

Updated on:April 12,2024 19

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit

Updated on: April 06,2024 0

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit

Updated on:April 06,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on: April 06,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on:April 06,2024 0