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Researchers pinpoint issue that could be hampering common chemotherapy drug

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche
Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa
New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r
Urine test halves painful procedures in bladder cancer follow up, new trial shows

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne
Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba
Tackling antibiotic resistance when treating pneumonia

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa
Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set
Researchers present playbook of best practices for cancer team science in the modern era

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat
Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki
The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
CRISPR-based mapping uncovers 'switches' for immune genes central to health

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t