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Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
New guidelines for reporting clinical trials of biofield therapies released

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem
Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec
Familial Alzheimer's disease transferred via bone marrow transplant in mice

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Alcohol may help flush out arsenic from the body, study finds

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i
Better MRI videos thanks to new machine learning method

Better MRI videos thanks to new machine learning method

by Philipp Jarke,Graz University of TechnologyShort-axis section through the heart: The simple MRI image reconstruction method "Gridding" (left), "RT-NLINV" method developed

Better MRI videos thanks to new machine learning method

by Philipp Jarke,Graz University of TechnologyShort-axis section through the heart: The simple MRI image reconstruction method "Gridding" (left), "RT-NLINV" method developed
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Competitive swimming program for young people with severe cerebral palsy reverses motor decline

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers
Key mechanism governing bone marrow stem cells opens door to new therapies

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod