Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Updated on: April 06,2024 0

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Updated on:April 06,2024 0

Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

JANUARY 23, 2024byUniversity Hospitals Cleveland Medical CenterCredit: Unsplash/CC0 Public DomainA recent study from researchers at University Hospitals (UH) Connor Whole Health has examined var

Updated on: March 28,2024 3

Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

JANUARY 23, 2024byUniversity Hospitals Cleveland Medical CenterCredit: Unsplash/CC0 Public DomainA recent study from researchers at University Hospitals (UH) Connor Whole Health has examined var

Updated on:March 28,2024 3

Baseline findings among hospitalized mucormycosis patients: A multicentric ambispective cohort study in India

FEBRUARY 6, 2024by Tsinghua University PressDirected acyclic graph demonstrating the relationship between potential risk factors of mortality due to mucormycosis. Credit: Dr. Rizwan Suliankatchi Abdul

Updated on: March 25,2024 7

Baseline findings among hospitalized mucormycosis patients: A multicentric ambispective cohort study in India

FEBRUARY 6, 2024by Tsinghua University PressDirected acyclic graph demonstrating the relationship between potential risk factors of mortality due to mucormycosis. Credit: Dr. Rizwan Suliankatchi Abdul

Updated on:March 25,2024 7

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on: April 28,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on:April 28,2024 0

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Updated on: March 30,2024 0

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Updated on:March 30,2024 0

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on: March 15,2024 8

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on:March 15,2024 8

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Updated on: June 18,2024 5

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Updated on:June 18,2024 5

A new immunologic and endocrine syndrome

by University of MontrealThese mice are twin, except that the left mouse is normal whereas the Armc5 gene has been invalidated by genetic knockout in the right mouse. The mutated mouse is smaller

Updated on: March 25,2024 12

A new immunologic and endocrine syndrome

by University of MontrealThese mice are twin, except that the left mouse is normal whereas the Armc5 gene has been invalidated by genetic knockout in the right mouse. The mutated mouse is smaller

Updated on:March 25,2024 12

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024 0

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024 0

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther

Updated on: April 18,2024 0

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther

Updated on:April 18,2024 0

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA

Updated on: April 27,2024 0

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA

Updated on:April 27,2024 0

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1