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Medical research
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Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Chemical and computational advances enable 2D proteomics measurements of spatial signals

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod
Serious flu damage prevented by compound that blocks unnecessary cell death

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the
New research into life-threatening birth defect of the diaphragm

New research into life-threatening birth defect of the diaphragm

by Birgit Pfeiffer,Leipzig UniversityHypoplastic lungs of human fetuses with CDH have increased macrophage density and up-regulation of inflammatory mediators. Credit:Science Advances&nbsp

New research into life-threatening birth defect of the diaphragm

by Birgit Pfeiffer,Leipzig UniversityHypoplastic lungs of human fetuses with CDH have increased macrophage density and up-regulation of inflammatory mediators. Credit:Science Advances&nbsp
Gene therapy gets a turbo boost from researchers

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease
Key mechanism governing bone marrow stem cells opens door to new therapies

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste
Wound healing checked in real time with electronic suture

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P
Common dry cleaning chemical linked to Parkinson's

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri