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Medical research
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Study finds embryos in hungry mouse moms postpone development

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,
Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th
How to make mRNA therapeutics safe from the start

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Insights into epigenetics: The humanized FKBP5 mouse as a model organism

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de
Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever
New insight into gene uncovers its link to incurable birth defect

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir
HIV: Early treatment is one key to remission

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-
Aspirin cuts liver fat in clinical trial

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an
Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

by Alvin Powell, Harvard GazetteCredit: Unsplash/CC0 Public DomainSome health care professionals are growing concerned that amid the recent rush for the new highly effective, anti-obesity medications,

Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

by Alvin Powell, Harvard GazetteCredit: Unsplash/CC0 Public DomainSome health care professionals are growing concerned that amid the recent rush for the new highly effective, anti-obesity medications,
One in five people with cancer participate in medical research studies

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n