Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024 0

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024 0

Researchers develop model to assess biology of human placental barrier

by Tokyo Medical and Dental UniversityPlacental organoids generated from human placental stem cells (left), a front view of the placental barrier model (center), and a side view of the barrier mo

Updated on: March 07,2024 6

Researchers develop model to assess biology of human placental barrier

by Tokyo Medical and Dental UniversityPlacental organoids generated from human placental stem cells (left), a front view of the placental barrier model (center), and a side view of the barrier mo

Updated on:March 07,2024 6

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024 0

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on: April 28,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on:April 28,2024 0

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on: April 28,2024 0

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on:April 28,2024 0

Doctors, apps and artificial intelligence - The future of medicine

Updated on: August 07,2024 0

Doctors, apps and artificial intelligence - The future of medicine

Updated on:August 07,2024 0

Cutting through the fog of long COVID

Updated on: November 09,2024 0

Cutting through the fog of long COVID

Updated on:November 09,2024 0

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Updated on: April 06,2024 0

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Updated on:April 06,2024 0

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on: June 15,2024 6

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on:June 15,2024 6

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model

Updated on: March 27,2024 0

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model

Updated on:March 27,2024 0

Study of data from thousands of women suggests ovarian cycle is regulated by circadian rhythm

by Bob Yirka , Medical XpressCredit: Puwadon Sang-ngern from PexelsA team of reproductive researchers affiliated with several institutions in France and the U.S. has found that the timing of monthly o

Updated on: April 28,2024 0

Study of data from thousands of women suggests ovarian cycle is regulated by circadian rhythm

by Bob Yirka , Medical XpressCredit: Puwadon Sang-ngern from PexelsA team of reproductive researchers affiliated with several institutions in France and the U.S. has found that the timing of monthly o

Updated on:April 28,2024 0

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1