Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on: March 15,2024 7

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on:March 15,2024 7

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Updated on: March 28,2024 0

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Updated on:March 28,2024 0

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on: March 25,2024 8

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on:March 25,2024 8

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on: March 30,2024 8

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on:March 30,2024 8

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc

Updated on: April 28,2024 0

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc

Updated on:April 28,2024 0

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024 0

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024 0

Cutting through the fog of long COVID

Updated on: November 09,2024 0

Cutting through the fog of long COVID

Updated on:November 09,2024 0

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on: April 26,2024 0

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on:April 26,2024 0

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on: March 25,2024 5

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on:March 25,2024 5

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on: August 12,2024 0

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on:August 12,2024 0

Making clinical guidelines work for large language models

by Rachel Martin,Yale UniversityExample of a clinical decision support system integrated with large language models. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01091-

Updated on: July 23,2024 0

Making clinical guidelines work for large language models

by Rachel Martin,Yale UniversityExample of a clinical decision support system integrated with large language models. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01091-

Updated on:July 23,2024 0