CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024 0

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024 0

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory

Updated on: March 28,2024 0

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory

Updated on:March 28,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on: April 06,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on:April 06,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on: March 28,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on:March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on: March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on:March 28,2024 0

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on: January 26,2024 7

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on:January 26,2024 7

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Updated on: March 28,2024 0

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Updated on:March 28,2024 0

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on: March 14,2024 11

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on:March 14,2024 11

Bowel Habits and Brain Power: Unveiling the Hidden Connection

Updated on: July 15,2024 0

Bowel Habits and Brain Power: Unveiling the Hidden Connection

Updated on:July 15,2024 0

A non-canonical mechanism for RNA damage compartmentalization and daughter cell protection

Updated on: August 08,2024 0

A non-canonical mechanism for RNA damage compartmentalization and daughter cell protection

Updated on:August 08,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on: April 23,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on:April 23,2024 0

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Updated on: January 26,2024 19

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Updated on:January 26,2024 19