Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on: May 08,2024 5

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on:May 08,2024 5

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired

Updated on: July 08,2024 0

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired

Updated on:July 08,2024 0

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Updated on: April 28,2024 0

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Updated on:April 28,2024 0

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024 0

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024 0

New study finds systematic biases at play in clinical trials

byMichigan State UniversityCredit: Pixabay/CC0 Public DomainRandomized controlled trials, or RCTs, are believed to be the best way to study the safety and efficacy of new treatments in clinical

Updated on: July 05,2024 0

New study finds systematic biases at play in clinical trials

byMichigan State UniversityCredit: Pixabay/CC0 Public DomainRandomized controlled trials, or RCTs, are believed to be the best way to study the safety and efficacy of new treatments in clinical

Updated on:July 05,2024 0

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n

Updated on: April 28,2024 0

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n

Updated on:April 28,2024 0

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on: July 05,2024 0

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on:July 05,2024 0

Gay and Bisexual Men Can Now Donate Blood—Why This Matters

Updated on: July 24,2024 0

Gay and Bisexual Men Can Now Donate Blood—Why This Matters

Updated on:July 24,2024 0

Patient images are missing in studies on atopic dermatitis

byUniversity of GothenburgPRISMA flow chart. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Credit:Journal of Dermatological Treatment(2024). DOI: 10.108

Updated on: April 28,2024 0

Patient images are missing in studies on atopic dermatitis

byUniversity of GothenburgPRISMA flow chart. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Credit:Journal of Dermatological Treatment(2024). DOI: 10.108

Updated on:April 28,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on: April 28,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on:April 28,2024 0

Tirzepatide versus Semaglutide in Weight Reduction

Clinical studies have demonstrated that both tirzepatide and semaglutide are effective in promoting weight loss among individuals with overweight or obesity.

Updated on: July 23,2024 0

Tirzepatide versus Semaglutide in Weight Reduction

Clinical studies have demonstrated that both tirzepatide and semaglutide are effective in promoting weight loss among individuals with overweight or obesity.

Updated on:July 23,2024 0

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on: April 28,2024 0

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on:April 28,2024 0