Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue

Updated on: December 28,2023 16

Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue

Updated on:December 28,2023 16

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a

Updated on: January 26,2024 8

Study suggests key to antipsychotic-drug–induced obesity

by UTSouthwestern Medical CenterEffect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or a

Updated on:January 26,2024 8

CRISPR treatment slows swelling in hereditary angioedema patients

by American College of Allergy, Asthma, and ImmunologyCredit: James atmos, CC BY-SA 3.0, via Wikimedia CommonsHereditary angioedema (HAE) is a rare, genetic disorder characterized by severe

Updated on: April 12,2024 19

CRISPR treatment slows swelling in hereditary angioedema patients

by American College of Allergy, Asthma, and ImmunologyCredit: James atmos, CC BY-SA 3.0, via Wikimedia CommonsHereditary angioedema (HAE) is a rare, genetic disorder characterized by severe

Updated on:April 12,2024 19

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on: January 02,2024 8

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on:January 02,2024 8

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Updated on: May 09,2024 4

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Updated on:May 09,2024 4

Experimental drug that alters gut microbiome shows promise for long COVID relief

by Mary Van Beusekom, CIDRAPProportion of PACS symptoms alleviation by six months. Credit:The Lancet Infectious Diseases(2023). DOI: 10.1016/S1473-3099(23)00685-0A randomized controlled tr

Updated on: January 26,2024 8

Experimental drug that alters gut microbiome shows promise for long COVID relief

by Mary Van Beusekom, CIDRAPProportion of PACS symptoms alleviation by six months. Credit:The Lancet Infectious Diseases(2023). DOI: 10.1016/S1473-3099(23)00685-0A randomized controlled tr

Updated on:January 26,2024 8

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Updated on: January 06,2024 15

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Updated on:January 06,2024 15

Sirtuin 6 activation rescues the age-related decline in DNA damage repair in chondrocytes: Study

by Impact Journals LLCExperimental design for the results shown in Figures 3 and 4. Credit: 2023 Copp et al.A newresearch papertitled "Sirtuin 6 activation rescues the age-related dec

Updated on: December 28,2023 7

Sirtuin 6 activation rescues the age-related decline in DNA damage repair in chondrocytes: Study

by Impact Journals LLCExperimental design for the results shown in Figures 3 and 4. Credit: 2023 Copp et al.A newresearch papertitled "Sirtuin 6 activation rescues the age-related dec

Updated on:December 28,2023 7

When are opioid prescription limits effective in reducing prescription duration?

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainMany states have passed new laws that place restrictions on the duration of first-time opioid prescriptions to help address the opioid

Updated on: March 22,2024 17

When are opioid prescription limits effective in reducing prescription duration?

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainMany states have passed new laws that place restrictions on the duration of first-time opioid prescriptions to help address the opioid

Updated on:March 22,2024 17

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Updated on: January 26,2024 12

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Updated on:January 26,2024 12

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a

Updated on: January 04,2024 5

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a

Updated on:January 04,2024 5

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on: January 06,2024 15

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on:January 06,2024 15