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Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
Study reveals potential to reverse lung fibrosis using the body's own healing technique

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop
Blood test can detect laughing gas and help the police fight whippit abuse

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas
Advancements in Digital Pathology: The Role of AI and Large Language Models

Advancements in Digital Pathology: The Role of AI and Large Language Models

While the advancements in AI and LLMs hold great promise for the field of digital pathology, it is essential to address the associated challenges and ethical considerations.

Advancements in Digital Pathology: The Role of AI and Large Language Models

While the advancements in AI and LLMs hold great promise for the field of digital pathology, it is essential to address the associated challenges and ethical considerations.
Patient images are missing in studies on atopic dermatitis

Patient images are missing in studies on atopic dermatitis

byUniversity of GothenburgPRISMA flow chart. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Credit:Journal of Dermatological Treatment(2024). DOI: 10.108

Patient images are missing in studies on atopic dermatitis

byUniversity of GothenburgPRISMA flow chart. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Credit:Journal of Dermatological Treatment(2024). DOI: 10.108
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.
Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired
Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin
Cockayne syndrome: New insights into cellular DNA repair mechanism

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma