Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on: April 02,2024 11

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on:April 02,2024 11

Plastic particles harm gut health and immunity in mice, study shows

by Zhang Nannan,Chinese Academy of SciencesEffect of PS-MNPs on the intestinal structure of mice. Representative images of H&E staining of mouse intestinal tissue. (A) Intestine of mice afte

Updated on: December 26,2023 15

Plastic particles harm gut health and immunity in mice, study shows

by Zhang Nannan,Chinese Academy of SciencesEffect of PS-MNPs on the intestinal structure of mice. Representative images of H&E staining of mouse intestinal tissue. (A) Intestine of mice afte

Updated on:December 26,2023 15

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on: March 28,2024 0

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on:March 28,2024 0

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b

Updated on: January 04,2024 12

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b

Updated on:January 04,2024 12

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on: April 30,2024 0

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on:April 30,2024 0

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on: May 05,2024 17

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on:May 05,2024 17

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Updated on: December 27,2023 12

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Updated on:December 27,2023 12

The Persistent Memory of Fat: How Obesity Leaves a Lasting Epigenetic Imprint

Updated on: November 22,2024 0

The Persistent Memory of Fat: How Obesity Leaves a Lasting Epigenetic Imprint

Updated on:November 22,2024 0

Pig Organ Transplants: Hope and Progress in Xenotransplantation

Updated on: May 25,2024 0

Pig Organ Transplants: Hope and Progress in Xenotransplantation

Updated on:May 25,2024 0

Circadian rhythms can influence drugs' effectiveness

by Anne Trafton,Massachusetts Institute of TechnologyPrimary human hepatocytes display a circadian rhythm in culture. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adm9281Giving

Updated on: April 28,2024 0

Circadian rhythms can influence drugs' effectiveness

by Anne Trafton,Massachusetts Institute of TechnologyPrimary human hepatocytes display a circadian rhythm in culture. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adm9281Giving

Updated on:April 28,2024 0

Scientists code ChatGPT to design new medicine

by Chapman UniversityGraphical abstract. Credit:Pharmaceuticals(2024). DOI: 10.3390/ph17020161Generative artificial intelligence platforms, from ChatGPT to Midjourney, grabbed headlin

Updated on: May 21,2024 5

Scientists code ChatGPT to design new medicine

by Chapman UniversityGraphical abstract. Credit:Pharmaceuticals(2024). DOI: 10.3390/ph17020161Generative artificial intelligence platforms, from ChatGPT to Midjourney, grabbed headlin

Updated on:May 21,2024 5