Research offers new insights into how breakdown of omega-6 fatty acids influences metabolism

by Eva Maria Wellnitz, Universitätsmedizin MannheimGeneration and validation of aldh9a1b−/- zebrafish line using CRISPR/Cas9 technology (A) Neighbor-joining phylogenetic bootstrap tree of amino acid s

Updated on: December 26,2023 8

Research offers new insights into how breakdown of omega-6 fatty acids influences metabolism

by Eva Maria Wellnitz, Universitätsmedizin MannheimGeneration and validation of aldh9a1b−/- zebrafish line using CRISPR/Cas9 technology (A) Neighbor-joining phylogenetic bootstrap tree of amino acid s

Updated on:December 26,2023 8

Cost cutting may be behind high levels of lead in recalled applesauce products

by Physician's Briefing StaffThe U.S. Food and Drug Administration is currently investigating whether or not the cinnamon used in applesauce pouches that have been tied to high lead levels in chil

Updated on: December 30,2023 14

Cost cutting may be behind high levels of lead in recalled applesauce products

by Physician's Briefing StaffThe U.S. Food and Drug Administration is currently investigating whether or not the cinnamon used in applesauce pouches that have been tied to high lead levels in chil

Updated on:December 30,2023 14

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the

Updated on: December 20,2023 10

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the

Updated on:December 20,2023 10

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

By analyzing brain stem cell data, Assistant Professor Christopher Plaisier and biomedical engineering doctoral student Samantha O'Connor saw the phases of the cell cycle mapped out in more detail

Updated on: November 02,2023 6

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

By analyzing brain stem cell data, Assistant Professor Christopher Plaisier and biomedical engineering doctoral student Samantha O'Connor saw the phases of the cell cycle mapped out in more detail

Updated on:November 02,2023 6

Circadian rhythms can influence drugs' effectiveness

by Anne Trafton,Massachusetts Institute of TechnologyPrimary human hepatocytes display a circadian rhythm in culture. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adm9281Giving

Updated on: April 28,2024 0

Circadian rhythms can influence drugs' effectiveness

by Anne Trafton,Massachusetts Institute of TechnologyPrimary human hepatocytes display a circadian rhythm in culture. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adm9281Giving

Updated on:April 28,2024 0

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on: May 05,2024 17

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on:May 05,2024 17

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on: April 30,2024 0

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on:April 30,2024 0

Pig Organ Transplants: Hope and Progress in Xenotransplantation

Updated on: May 25,2024 0

Pig Organ Transplants: Hope and Progress in Xenotransplantation

Updated on:May 25,2024 0

Brain cell discovery sparks hope for fertility treatments

byNagoya UniversityResearchers demonstrated kisspeptin neurons with dynorphin receptors in the brain affects the release of hormones that affect reproductive function in females. Credit: Mayuko

Updated on: December 26,2023 16

Brain cell discovery sparks hope for fertility treatments

byNagoya UniversityResearchers demonstrated kisspeptin neurons with dynorphin receptors in the brain affects the release of hormones that affect reproductive function in females. Credit: Mayuko

Updated on:December 26,2023 16

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Updated on: December 27,2023 12

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Updated on:December 27,2023 12

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefits

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefitsby Lauren Ball and Emily Burch,The ConversationCredit: Unsplash/CC0 Public DomainAfter weight-loss d

Updated on: April 06,2024 0

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefits

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefitsby Lauren Ball and Emily Burch,The ConversationCredit: Unsplash/CC0 Public DomainAfter weight-loss d

Updated on:April 06,2024 0