Designing a normative neuroimaging library to support diagnosis of traumatic brain injury

byMary Ann Liebert, IncCredit: Wikimedia CommonsWith recent advances in neuroimaging, moving from qualitative to quantitative outputs, an understanding is needed of what normal data look like to

Updated on: September 23,2024

Designing a normative neuroimaging library to support diagnosis of traumatic brain injury

byMary Ann Liebert, IncCredit: Wikimedia CommonsWith recent advances in neuroimaging, moving from qualitative to quantitative outputs, an understanding is needed of what normal data look like to

Updated on:September 23,2024

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on: April 07,2024

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on:April 07,2024

PET scans for Alzheimer's could bring benefit to more patients

by Ryan O'hare,Imperial College LondonPET scans can spot amyloid in the brain (pictured). Credit: Imperial College LondonAn imaging tool honed to spot rogue proteins in the brain could benef

Updated on: April 01,2024

PET scans for Alzheimer's could bring benefit to more patients

by Ryan O'hare,Imperial College LondonPET scans can spot amyloid in the brain (pictured). Credit: Imperial College LondonAn imaging tool honed to spot rogue proteins in the brain could benef

Updated on:April 01,2024

Study highlights financial burden of dementia on older adults, families

by Sam Fahmy,Georgia State UniversityCredit: Kampus Production from PexelsA new study that provides details on out-of-pocket expenses for people with dementia finds that costs for long-term care

Updated on: March 08,2024

Study highlights financial burden of dementia on older adults, families

by Sam Fahmy,Georgia State UniversityCredit: Kampus Production from PexelsA new study that provides details on out-of-pocket expenses for people with dementia finds that costs for long-term care

Updated on:March 08,2024

Cause of Alzheimer's disease traced to mutation in common enzyme

by Tokyo Metropolitan UniversityThe mutant MARK4 creates a form of tau which accumulates easily in brain cells, causing neurons to die. Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metr

Updated on: April 07,2024

Cause of Alzheimer's disease traced to mutation in common enzyme

by Tokyo Metropolitan UniversityThe mutant MARK4 creates a form of tau which accumulates easily in brain cells, causing neurons to die. Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metr

Updated on:April 07,2024

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on: April 07,2024

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on:April 07,2024

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on: November 22,2024

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on:November 22,2024

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on: April 10,2024

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on:April 10,2024

Alzheimer's disease biomarkers can predict postoperative delirium

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainClinical studies have demonstrated a strong association between Alzheimer's disease (AD) and delirium. A change to the Tau p

Updated on: April 07,2024

Alzheimer's disease biomarkers can predict postoperative delirium

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainClinical studies have demonstrated a strong association between Alzheimer's disease (AD) and delirium. A change to the Tau p

Updated on:April 07,2024

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on: November 22,2024

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on:November 22,2024

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on: April 10,2024

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on:April 10,2024

Concussed athletes' brains benefit from just 20 minutes of exercise

Updated on: March 05,2025

Concussed athletes' brains benefit from just 20 minutes of exercise

Updated on:March 05,2025