Cause of Alzheimer's disease traced to mutation in common enzyme

by Tokyo Metropolitan UniversityThe mutant MARK4 creates a form of tau which accumulates easily in brain cells, causing neurons to die. Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metr

Updated on: April 07,2024

Cause of Alzheimer's disease traced to mutation in common enzyme

by Tokyo Metropolitan UniversityThe mutant MARK4 creates a form of tau which accumulates easily in brain cells, causing neurons to die. Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metr

Updated on:April 07,2024

New study finds cell donor's socioeconomic status shapes cancer treatment outcomes

by Alex Smith,University of Minnesota Medical SchoolCredit: Pixabay/CC0 Public DomainA research team led by the University of Minnesota Medical School demonstrated that the socioeconomic status

Updated on: August 01,2024

New study finds cell donor's socioeconomic status shapes cancer treatment outcomes

by Alex Smith,University of Minnesota Medical SchoolCredit: Pixabay/CC0 Public DomainA research team led by the University of Minnesota Medical School demonstrated that the socioeconomic status

Updated on:August 01,2024

Alzheimer's disease biomarkers can predict postoperative delirium

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainClinical studies have demonstrated a strong association between Alzheimer's disease (AD) and delirium. A change to the Tau p

Updated on: April 07,2024

Alzheimer's disease biomarkers can predict postoperative delirium

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainClinical studies have demonstrated a strong association between Alzheimer's disease (AD) and delirium. A change to the Tau p

Updated on:April 07,2024

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on: April 07,2024

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on:April 07,2024

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on: April 10,2024

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on:April 10,2024

PET scans for Alzheimer's could bring benefit to more patients

by Ryan O'hare,Imperial College LondonPET scans can spot amyloid in the brain (pictured). Credit: Imperial College LondonAn imaging tool honed to spot rogue proteins in the brain could benef

Updated on: April 01,2024

PET scans for Alzheimer's could bring benefit to more patients

by Ryan O'hare,Imperial College LondonPET scans can spot amyloid in the brain (pictured). Credit: Imperial College LondonAn imaging tool honed to spot rogue proteins in the brain could benef

Updated on:April 01,2024

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on: April 10,2024

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on:April 10,2024

Tracing brain circuits that tell us when to eat—and when to stop

Updated on: July 07,2025

Tracing brain circuits that tell us when to eat—and when to stop

Updated on:July 07,2025

Brain stimulation did not improve impaired motor skills after stroke: Clinical trial

Updated on: February 28,2025

Brain stimulation did not improve impaired motor skills after stroke: Clinical trial

Updated on:February 28,2025

Study highlights financial burden of dementia on older adults, families

by Sam Fahmy,Georgia State UniversityCredit: Kampus Production from PexelsA new study that provides details on out-of-pocket expenses for people with dementia finds that costs for long-term care

Updated on: March 08,2024

Study highlights financial burden of dementia on older adults, families

by Sam Fahmy,Georgia State UniversityCredit: Kampus Production from PexelsA new study that provides details on out-of-pocket expenses for people with dementia finds that costs for long-term care

Updated on:March 08,2024

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on: April 07,2024

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on:April 07,2024

A new culprit of cognitive decline in Alzheimer's disease

by Julie Langelier,Gladstone InstitutesPET scan of a human brain with Alzheimer's disease. Credit: public domainIt has long been known that patients with Alzheimer's disease have abnorma

Updated on: April 10,2024

A new culprit of cognitive decline in Alzheimer's disease

by Julie Langelier,Gladstone InstitutesPET scan of a human brain with Alzheimer's disease. Credit: public domainIt has long been known that patients with Alzheimer's disease have abnorma

Updated on:April 10,2024