DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on: October 14,2024

DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on:October 14,2024

Drug target for Alzheimer's disease has dual action

by Queensland Brain InstituteCredit: Queensland Brain InstituteResearchers have discovered a potential drug target for Alzheimer's disease—an enzyme which has effects on both the immune and nervou

Updated on: April 16,2024

Drug target for Alzheimer's disease has dual action

by Queensland Brain InstituteCredit: Queensland Brain InstituteResearchers have discovered a potential drug target for Alzheimer's disease—an enzyme which has effects on both the immune and nervou

Updated on:April 16,2024

Discouraged zebrafish help reveal how ketamine works in the brain

byHoward Hughes Medical InstituteCredit: Duque, Chen, Hsu, et al.The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions ab

Updated on: January 19,2025

Discouraged zebrafish help reveal how ketamine works in the brain

byHoward Hughes Medical InstituteCredit: Duque, Chen, Hsu, et al.The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions ab

Updated on:January 19,2025

Fruit fly study provides a blueprint for the brain's circadian clock

byJulius-Maximilians-Universität WürzburgImage showing all the neurons (color-coded based on type) that make up the Drosophila circadian clock network. Credit: Nils ReinhardCircadian clocks cont

Updated on: December 17,2024

Fruit fly study provides a blueprint for the brain's circadian clock

byJulius-Maximilians-Universität WürzburgImage showing all the neurons (color-coded based on type) that make up the Drosophila circadian clock network. Credit: Nils ReinhardCircadian clocks cont

Updated on:December 17,2024

Brain injury rehabilitation study reveals neural mechanisms of sleep-dependent motor learning

by Kessler FoundationCredit: Pixabay/CC0 Public DomainNew research published by scientists at Kessler Foundation provides critical insights into the role of sleep in motor learning for individuals rec

Updated on: November 27,2024

Brain injury rehabilitation study reveals neural mechanisms of sleep-dependent motor learning

by Kessler FoundationCredit: Pixabay/CC0 Public DomainNew research published by scientists at Kessler Foundation provides critical insights into the role of sleep in motor learning for individuals rec

Updated on:November 27,2024

Study highlights complexity of menopausal hormone therapy's impact on brain health

byeLifeAssociations between brain MRI measures and MHT user status. Credit:(2024). DOI: 10.7554/eLife.99538.1A study suggests that menopausal hormone therapy (MHT) might have moderate effe

Updated on: November 06,2024

Study highlights complexity of menopausal hormone therapy's impact on brain health

byeLifeAssociations between brain MRI measures and MHT user status. Credit:(2024). DOI: 10.7554/eLife.99538.1A study suggests that menopausal hormone therapy (MHT) might have moderate effe

Updated on:November 06,2024

Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on: February 28,2024

Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on:February 28,2024

FDA panel urges rejection of experimental Alzheimer's drug

by Marilynn Marchione and Matthew PerroneIn this Dec. 12, 2019 photo provided by Biogen, a scientist works on Alzheimer's disease research in a laboratory at the drugmaker's headquarters in Ca

Updated on: March 30,2024

FDA panel urges rejection of experimental Alzheimer's drug

by Marilynn Marchione and Matthew PerroneIn this Dec. 12, 2019 photo provided by Biogen, a scientist works on Alzheimer's disease research in a laboratory at the drugmaker's headquarters in Ca

Updated on:March 30,2024

The link between headache disorders and suicide—a 25-year Danish cohort study

by Justin Jackson , Medical XpressCredit: Kindel Media from PexelsNew evidence from a large population-based cohort analysis indicates an increased risk of both attempted and completed suicide among i

Updated on: February 23,2025

The link between headache disorders and suicide—a 25-year Danish cohort study

by Justin Jackson , Medical XpressCredit: Kindel Media from PexelsNew evidence from a large population-based cohort analysis indicates an increased risk of both attempted and completed suicide among i

Updated on:February 23,2025

Genes that may protect against dementia

by Ricki Lewis, Phd,Public Library of Science"Survival of the fittest" is one of the most misunderstood terms in biology. Evoking images of physical prowess, it actually refers to an i

Updated on: February 27,2024

Genes that may protect against dementia

by Ricki Lewis, Phd,Public Library of Science"Survival of the fittest" is one of the most misunderstood terms in biology. Evoking images of physical prowess, it actually refers to an i

Updated on:February 27,2024

Scientists use DNA methylation patterns as roadmap for identifying causes of severe epilepsies in children

bySt. Jude Children's Research HospitalDescription of the DNA methylation analysis and features of the study cohort. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5

Updated on: August 08,2024

Scientists use DNA methylation patterns as roadmap for identifying causes of severe epilepsies in children

bySt. Jude Children's Research HospitalDescription of the DNA methylation analysis and features of the study cohort. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5

Updated on:August 08,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024