Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on: February 28,2024

Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on:February 28,2024

Alzheimer's and aducanumab: Unjust profits and false hopes

by The Hastings CenterCredit: CC0 Public DomainThe U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at leas

Updated on: April 08,2024

Alzheimer's and aducanumab: Unjust profits and false hopes

by The Hastings CenterCredit: CC0 Public DomainThe U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at leas

Updated on:April 08,2024

FDA panel urges rejection of experimental Alzheimer's drug

by Marilynn Marchione and Matthew PerroneIn this Dec. 12, 2019 photo provided by Biogen, a scientist works on Alzheimer's disease research in a laboratory at the drugmaker's headquarters in Ca

Updated on: March 30,2024

FDA panel urges rejection of experimental Alzheimer's drug

by Marilynn Marchione and Matthew PerroneIn this Dec. 12, 2019 photo provided by Biogen, a scientist works on Alzheimer's disease research in a laboratory at the drugmaker's headquarters in Ca

Updated on:March 30,2024

New study reveals immune protein's critical role in neuronal function and aging

New study reveals immune protein's critical role in neuronal function and agingbyChildren's Hospital BostonMicroglial-derived C1q integrates into neuronal ribonucleoprotein complexes and

Updated on: July 17,2024

New study reveals immune protein's critical role in neuronal function and aging

New study reveals immune protein's critical role in neuronal function and agingbyChildren's Hospital BostonMicroglial-derived C1q integrates into neuronal ribonucleoprotein complexes and

Updated on:July 17,2024

First human vagus nerve recordings pinpoint cardiovascular signals

byMonash UniversityCredit:The Journal of Physiology(2024). DOI: 10.1113/JP286423The team that first recorded vagus nerve signals in humans has now isolated the electrical activity of

Updated on: October 14,2024

First human vagus nerve recordings pinpoint cardiovascular signals

byMonash UniversityCredit:The Journal of Physiology(2024). DOI: 10.1113/JP286423The team that first recorded vagus nerve signals in humans has now isolated the electrical activity of

Updated on:October 14,2024

Dementia study reveals how proteins interact to stop brain signals

by University of EdinburghCredit: CC0 Public DomainFresh insights into damaging proteins that build up in the brains of people with Alzheimer's disease could aid the quest for treatments.A st

Updated on: May 11,2024

Dementia study reveals how proteins interact to stop brain signals

by University of EdinburghCredit: CC0 Public DomainFresh insights into damaging proteins that build up in the brains of people with Alzheimer's disease could aid the quest for treatments.A st

Updated on:May 11,2024

Dementia perceived as "illness" rather than aging symptom can lower mood

by Louise Vennells,University of ExeterPeople who perceive dementia symptoms as an illness feel more negative than those who see it as an inevitable part of getting older, a new study indicates.

Updated on: February 28,2024

Dementia perceived as "illness" rather than aging symptom can lower mood

by Louise Vennells,University of ExeterPeople who perceive dementia symptoms as an illness feel more negative than those who see it as an inevitable part of getting older, a new study indicates.

Updated on:February 28,2024

What are the early signs of dementia, and how does it differ from normal aging?

by Lachlan Gilbert,University of New South WalesCredit: Pixabay/CC0 Public DomainForgetting names and misplacing items happen to us all, more so as we age.But when should you be concerned that t

Updated on: March 08,2024

What are the early signs of dementia, and how does it differ from normal aging?

by Lachlan Gilbert,University of New South WalesCredit: Pixabay/CC0 Public DomainForgetting names and misplacing items happen to us all, more so as we age.But when should you be concerned that t

Updated on:March 08,2024

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on: March 30,2024

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on:March 30,2024

MouseGoggles offer immersive look into neural activity

MouseGoggles offer immersive look into neural activityby David Nutt,Cornell UniversityCornell researchers built miniature VR headsets to immerse mice more deeply in virtual environments that can

Updated on: January 18,2025

MouseGoggles offer immersive look into neural activity

MouseGoggles offer immersive look into neural activityby David Nutt,Cornell UniversityCornell researchers built miniature VR headsets to immerse mice more deeply in virtual environments that can

Updated on:January 18,2025

Experimental study in rats and humans show cognitive effort whets the appetite for reward

by PNAS NexusEffects of cognitive effort without rest on cocaine self-administration. Experimental design (A), time course (B) and average in the last 3 days of self-administration (C) of number of in

Updated on: November 07,2024

Experimental study in rats and humans show cognitive effort whets the appetite for reward

by PNAS NexusEffects of cognitive effort without rest on cocaine self-administration. Experimental design (A), time course (B) and average in the last 3 days of self-administration (C) of number of in

Updated on:November 07,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024