An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Study unveils new insights into how neural stem cells are activated in the adult human brain

Updated on: February 28,2025

Study unveils new insights into how neural stem cells are activated in the adult human brain

Updated on:February 28,2025

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on: February 26,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on:February 26,2024

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on: October 16,2024

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on:October 16,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on: March 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on:March 28,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on: April 16,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on:April 16,2024

Multiple sclerosis brain atlas could pave way for personalized treatments

by Anne Hammarskjöld,Karolinska InstitutetGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.11.016An international research team, including researchers at Karolinsk

Updated on: January 08,2025

Multiple sclerosis brain atlas could pave way for personalized treatments

by Anne Hammarskjöld,Karolinska InstitutetGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.11.016An international research team, including researchers at Karolinsk

Updated on:January 08,2025

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on: March 02,2024

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on:March 02,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on: April 08,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on:April 08,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on: February 28,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on:February 28,2024

Abnormal hyperactivation in the brain may be an early sign of Alzheimer's

by Salle de Presse,University of MontrealCredit: Unsplash/CC0 Public DomainAbnormally hyperactive areas in the brain may help better predict the onset of Alzheimer's disease, according to fi

Updated on: May 18,2024

Abnormal hyperactivation in the brain may be an early sign of Alzheimer's

by Salle de Presse,University of MontrealCredit: Unsplash/CC0 Public DomainAbnormally hyperactive areas in the brain may help better predict the onset of Alzheimer's disease, according to fi

Updated on:May 18,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on: March 07,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on:March 07,2024