Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on: August 08,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on:August 08,2024

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease

by Perelman School of Medicine at the University of PennsylvaniaCoronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of hum

Updated on: March 13,2024

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease

by Perelman School of Medicine at the University of PennsylvaniaCoronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of hum

Updated on:March 13,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on: April 20,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on:April 20,2024

Significant correlation found between vitreous human biomarkers and Alzheimer's disease

by Boston Medical CenterBoxplots of vitreous fluid biomarkers levels of total Tau, by study groups, compared using Kruskal-Wallis rank sum test withpvalues adjusted for multiple compa

Updated on: April 29,2024

Significant correlation found between vitreous human biomarkers and Alzheimer's disease

by Boston Medical CenterBoxplots of vitreous fluid biomarkers levels of total Tau, by study groups, compared using Kruskal-Wallis rank sum test withpvalues adjusted for multiple compa

Updated on:April 29,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on: February 28,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on:February 28,2024

New project focuses on dementia in farming and rural communities

by Andrew Gould,University of PlymouthDementia is a growing health problem, with an anticipated increase in the number of cases of 156 per cent between now and 2051, according to statistics from

Updated on: February 28,2024

New project focuses on dementia in farming and rural communities

by Andrew Gould,University of PlymouthDementia is a growing health problem, with an anticipated increase in the number of cases of 156 per cent between now and 2051, according to statistics from

Updated on:February 28,2024

Benzodiazepines increase mortality in persons with Alzheimer's disease

by University of Eastern FinlandBenzodiazepine and related drug use is associated with a 40 percent increase in mortality among persons with Alzheimer's disease, according to a new study from

Updated on: March 07,2024

Benzodiazepines increase mortality in persons with Alzheimer's disease

by University of Eastern FinlandBenzodiazepine and related drug use is associated with a 40 percent increase in mortality among persons with Alzheimer's disease, according to a new study from

Updated on:March 07,2024

FDA defends approval of controversial Alzheimer's drug

by Dennis ThompsonThe U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defendi

Updated on: March 30,2024

FDA defends approval of controversial Alzheimer's drug

by Dennis ThompsonThe U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defendi

Updated on:March 30,2024

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci

Updated on: July 01,2024

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci

Updated on:July 01,2024

GOSH BRC Showcase 2025 - Genomic medicine

Updated on: November 06,2025

GOSH BRC Showcase 2025 - Genomic medicine

Updated on:November 06,2025

rTMS as a treatment for Veterans with cognitive impairment and multiple co-morbidities

by IOS PressSchematic of a typical rTMS setup. Credit: Dr. ChengCurrent treatments for Alzheimer's disease are of limited effectiveness and do not halt the progression of the disease and asso

Updated on: March 09,2024

rTMS as a treatment for Veterans with cognitive impairment and multiple co-morbidities

by IOS PressSchematic of a typical rTMS setup. Credit: Dr. ChengCurrent treatments for Alzheimer's disease are of limited effectiveness and do not halt the progression of the disease and asso

Updated on:March 09,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024