Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Blueberries, the well-known 'super fruit,' could help fight Alzheimer's

by American Chemical SocietyA maturing 'Polaris' blueberry (Vaccinium corymbosum) Credit: Public DomainThe blueberry, already labeled a 'super fruit' for its power to potentially

Updated on: February 28,2024

Blueberries, the well-known 'super fruit,' could help fight Alzheimer's

by American Chemical SocietyA maturing 'Polaris' blueberry (Vaccinium corymbosum) Credit: Public DomainThe blueberry, already labeled a 'super fruit' for its power to potentially

Updated on:February 28,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on: May 18,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on:May 18,2024

Antidepressant use increases risk of head injuries among persons with Alzheimer's disease

by University of Eastern FinlandAntidepressant use is associated with an increased risk of head injuries and traumatic brain injuries among persons with Alzheimer's disease, according to a ne

Updated on: March 07,2024

Antidepressant use increases risk of head injuries among persons with Alzheimer's disease

by University of Eastern FinlandAntidepressant use is associated with an increased risk of head injuries and traumatic brain injuries among persons with Alzheimer's disease, according to a ne

Updated on:March 07,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on: February 28,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on:February 28,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on: April 16,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on:April 16,2024

New tools reveal neuropeptides, not neurotransmitters, encode danger in the brain

bySalk InstituteTwo images of nerve endings in the amygdala (where fear signals are received and interpreted). On the left, there are no labels and two distinct vesicles in the nerve endings can

Updated on: July 30,2024

New tools reveal neuropeptides, not neurotransmitters, encode danger in the brain

bySalk InstituteTwo images of nerve endings in the amygdala (where fear signals are received and interpreted). On the left, there are no labels and two distinct vesicles in the nerve endings can

Updated on:July 30,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on: May 11,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on:May 11,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

The cloud facilitates independent living for the elderly

by CORDISCredit: Maria Fernanda Cabrera UmpiérrezAging can be accompanied by cognitive deterioration that may affect life quality and possibly safety. EU research has developed a range of ICT sol

Updated on: March 09,2024

The cloud facilitates independent living for the elderly

by CORDISCredit: Maria Fernanda Cabrera UmpiérrezAging can be accompanied by cognitive deterioration that may affect life quality and possibly safety. EU research has developed a range of ICT sol

Updated on:March 09,2024