Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on: March 09,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on:March 09,2024

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on: February 28,2024

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on:February 28,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on: March 13,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on:March 13,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on: February 27,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on:February 27,2024

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on: February 05,2024

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on:February 05,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease

by Perelman School of Medicine at the University of PennsylvaniaCoronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of hum

Updated on: March 13,2024

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease

by Perelman School of Medicine at the University of PennsylvaniaCoronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of hum

Updated on:March 13,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on: February 05,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on:February 05,2024

Precision medicine data dive shows water pill may be viable to test as Alzheimer's treatment

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainA commonly available oral diuretic pill approved by the U.S. Food and Drug Administrat

Updated on: July 04,2024

Precision medicine data dive shows water pill may be viable to test as Alzheimer's treatment

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainA commonly available oral diuretic pill approved by the U.S. Food and Drug Administrat

Updated on:July 04,2024