Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on: February 28,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on:February 28,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on: April 16,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on:April 16,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on: June 24,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on:June 24,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on: March 07,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on:March 07,2024

Tackling the ethical considerations of dementia research

by Marilyn Perkins,University of PennsylvaniaPositron emission tomography (PET) scans similar to the one above can use a harmless radioactive tracer to visualize levels of amyloid in the brain.

Updated on: July 01,2024

Tackling the ethical considerations of dementia research

by Marilyn Perkins,University of PennsylvaniaPositron emission tomography (PET) scans similar to the one above can use a harmless radioactive tracer to visualize levels of amyloid in the brain.

Updated on:July 01,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on: July 01,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on:July 01,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on: February 05,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on:February 05,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on: March 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on:March 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024