Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on: July 01,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on:July 01,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on: February 27,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on:February 27,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on: February 05,2024

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on:February 05,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on: April 08,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on:April 08,2024

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on: February 28,2024

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on:February 28,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on: March 07,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on:March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on: February 28,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on:February 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on: May 18,2024

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on:May 18,2024