Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024 13

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024 13

Lipid and glucose levels at age 35 associated with Alzheimer's disease

by Boston University School of MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainLiving your best life at 35, ignoring cholesterol and glucose levels, may impac

Updated on: March 13,2024 17

Lipid and glucose levels at age 35 associated with Alzheimer's disease

by Boston University School of MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainLiving your best life at 35, ignoring cholesterol and glucose levels, may impac

Updated on:March 13,2024 17

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20

Brain takes a beating as arteries age

by Umea UniversityCredit: CC0 Public DomainResearchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased lo

Updated on: May 20,2024 8

Brain takes a beating as arteries age

by Umea UniversityCredit: CC0 Public DomainResearchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased lo

Updated on:May 20,2024 8

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024 0

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024 0

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on: February 26,2024 13

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on:February 26,2024 13

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on: February 05,2024 17

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on:February 05,2024 17

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on: March 09,2024 11

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on:March 09,2024 11

No clinical symptoms in study of Alzheimer's transmissibility

by Medical University of ViennaMedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer's disease. Although the prote

Updated on: February 28,2024 13

No clinical symptoms in study of Alzheimer's transmissibility

by Medical University of ViennaMedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer's disease. Although the prote

Updated on:February 28,2024 13

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on: March 07,2024 11

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on:March 07,2024 11

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on: May 13,2024 3

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on:May 13,2024 3

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on: February 27,2024 15

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on:February 27,2024 15