Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on: November 22,2024

Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on:November 22,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

Neuroscientists map how the brain transforms sensation into action

bySainsbury Wellcome CentreResearchers map how the brain transforms sensation into action. Credit: Sainsbury Wellcome CentreNeuroscientists have revealed how sensory input is transformed into mo

Updated on: September 23,2024

Neuroscientists map how the brain transforms sensation into action

bySainsbury Wellcome CentreResearchers map how the brain transforms sensation into action. Credit: Sainsbury Wellcome CentreNeuroscientists have revealed how sensory input is transformed into mo

Updated on:September 23,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024

Blood markers of brain cell damage higher over short term in COVID-19 patients than in Alzheimer's patients

by NYU Langone HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainPatients hospitalized for COVID-19 had higher levels over the short term of blood proteins known

Updated on: May 22,2024

Blood markers of brain cell damage higher over short term in COVID-19 patients than in Alzheimer's patients

by NYU Langone HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainPatients hospitalized for COVID-19 had higher levels over the short term of blood proteins known

Updated on:May 22,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on: March 07,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on:March 07,2024

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on: March 30,2024

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on:March 30,2024

Alzheimer's progression tied to stress-induced microglial lipid release

byCUNY Advanced Science Research CenterElectron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia of a 91-year-old female pati

Updated on: January 18,2025

Alzheimer's progression tied to stress-induced microglial lipid release

byCUNY Advanced Science Research CenterElectron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia of a 91-year-old female pati

Updated on:January 18,2025

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on: February 26,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on:February 26,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on: November 27,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on:November 27,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on: April 08,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on:April 08,2024