Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on: March 09,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on:March 09,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Panel of 48 CSF proteins complements existing Alzheimer biomarkers

by Elana GotkineA panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of&

Updated on: March 02,2024

Panel of 48 CSF proteins complements existing Alzheimer biomarkers

by Elana GotkineA panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of&

Updated on:March 02,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on: February 18,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on:February 18,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024