Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on: February 27,2024

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on:February 27,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on: February 05,2024

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on:February 05,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on: September 23,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on:September 23,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on: May 21,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on:May 21,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on: May 13,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on:May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on: May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on:May 13,2024

How common nutritional supplements may protect against traumatic brain injuries in sports

by Max Esterhuizen,Virginia TechCredit: Pixabay/CC0 Public DomainThe pouring rain and blustery wind gusts are brutal. The crowd is bone-chillingly cold, but they don't care.Their favorite fo

Updated on: February 05,2024

How common nutritional supplements may protect against traumatic brain injuries in sports

by Max Esterhuizen,Virginia TechCredit: Pixabay/CC0 Public DomainThe pouring rain and blustery wind gusts are brutal. The crowd is bone-chillingly cold, but they don't care.Their favorite fo

Updated on:February 05,2024