Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Key gene in familial Alzheimer's disease regulates neuronal development

by Autonomous University of BarcelonaAn international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differe

Updated on: March 07,2024

Key gene in familial Alzheimer's disease regulates neuronal development

by Autonomous University of BarcelonaAn international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differe

Updated on:March 07,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on: March 09,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on:March 09,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on: April 29,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on:April 29,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on: February 21,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on:February 21,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on: August 08,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on:August 08,2024

Ultrasound brain stimulation slows dementia-related brain degeneration

by Medical University of ViennaBrain–behavior correlations. A, Regions of interest—namely left superior parietal lobule (SPL) and left precuneus—where a significant correlation (plotted in panel

Updated on: May 06,2024

Ultrasound brain stimulation slows dementia-related brain degeneration

by Medical University of ViennaBrain–behavior correlations. A, Regions of interest—namely left superior parietal lobule (SPL) and left precuneus—where a significant correlation (plotted in panel

Updated on:May 06,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024