A recurrent neural network-based framework to non-linearly model behaviorally relevant neural dynamics

by Ingrid Fadelli , Medical XpressDPAD overview. Credit: Sani, Pesaran & Shanechi.A key objective of several neuroscience studies is to understand and model how the dynamics of distinct population

Updated on: October 16,2024

A recurrent neural network-based framework to non-linearly model behaviorally relevant neural dynamics

by Ingrid Fadelli , Medical XpressDPAD overview. Credit: Sani, Pesaran & Shanechi.A key objective of several neuroscience studies is to understand and model how the dynamics of distinct population

Updated on:October 16,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on: March 30,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on:March 30,2024

Researchers identify genetic factors that contribute to Alzheimer's disease

by Boston University School of MedicineResearchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in t

Updated on: March 07,2024

Researchers identify genetic factors that contribute to Alzheimer's disease

by Boston University School of MedicineResearchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in t

Updated on:March 07,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on: February 27,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on:February 27,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on: March 19,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on:March 19,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on: June 24,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on:June 24,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on: April 25,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on:April 25,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on: March 28,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on:March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024