Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on: August 01,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on:August 01,2024

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on: February 27,2024

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on:February 27,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on: September 23,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on:September 23,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Chronic musculoskeletal pain may accelerate brain aging

byChinese Academy of SciencesChronic pain leads to accelerated brain aging. Credit: Xie RuiIn a studypublishedinNature Mental Health, scientists from China and the United State

Updated on: March 28,2024

Chronic musculoskeletal pain may accelerate brain aging

byChinese Academy of SciencesChronic pain leads to accelerated brain aging. Credit: Xie RuiIn a studypublishedinNature Mental Health, scientists from China and the United State

Updated on:March 28,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on: August 08,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on:August 08,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on: May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on:May 13,2024