A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on: August 01,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on:August 01,2024

Neuroscientists map how the brain transforms sensation into action

bySainsbury Wellcome CentreResearchers map how the brain transforms sensation into action. Credit: Sainsbury Wellcome CentreNeuroscientists have revealed how sensory input is transformed into mo

Updated on: September 23,2024

Neuroscientists map how the brain transforms sensation into action

bySainsbury Wellcome CentreResearchers map how the brain transforms sensation into action. Credit: Sainsbury Wellcome CentreNeuroscientists have revealed how sensory input is transformed into mo

Updated on:September 23,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on: November 27,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on:November 27,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on: April 29,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on:April 29,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on: August 08,2024

Study reveals next frontier in reproducible brain imaging for neuroscience discovery

by The Child Mind InstituteCredit: Pixabay/CC0 Public DomainThe Child Mind Institute has released a paper detailing their pioneering study in the journalNature Human Behaviourtitled, &quot

Updated on:August 08,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on: March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on:March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on: May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on:May 13,2024