Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on: February 05,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on:February 05,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on: February 18,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on:February 18,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on: March 19,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on:March 19,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on: March 09,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on:March 09,2024