Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on: March 02,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on:March 02,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on: February 26,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on:February 26,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on: April 08,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on:April 08,2024

Alzheimer's memory discovery reveals function of brain area affected at onset

by University of St AndrewsCredit: CC0 Public DomainScientists at the Universities of St Andrews and Edinburgh have discovered the functions of the area of the brain in which Alzheimer's begi

Updated on: April 18,2024

Alzheimer's memory discovery reveals function of brain area affected at onset

by University of St AndrewsCredit: CC0 Public DomainScientists at the Universities of St Andrews and Edinburgh have discovered the functions of the area of the brain in which Alzheimer's begi

Updated on:April 18,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on: March 28,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on:March 28,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Arterial stiffening linked to Alzheimer's disease

by Paul Govern,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainA research team from Vanderbilt University Medical Center reports inNeurologythat greater stiffening of the aorta

Updated on: May 22,2024

Arterial stiffening linked to Alzheimer's disease

by Paul Govern,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainA research team from Vanderbilt University Medical Center reports inNeurologythat greater stiffening of the aorta

Updated on:May 22,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024