Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024

Our minds drift more as tasks drag on, researchers find

by Kyra Gurney,University of MiamiCredit: Pixabay/CC0 Public DomainThe longer a person spends on a task, the more their mind starts to wander—regardless of whether the activity is difficult or

Updated on: March 19,2024

Our minds drift more as tasks drag on, researchers find

by Kyra Gurney,University of MiamiCredit: Pixabay/CC0 Public DomainThe longer a person spends on a task, the more their mind starts to wander—regardless of whether the activity is difficult or

Updated on:March 19,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on: May 06,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on:May 06,2024

Closed-eye imaging can track wakefulness, awareness and pain in unresponsive conditions

byTel-Aviv UniversityPupillary light reflex (PLR) assessment in open-eye and closed-eye conditions. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00572-1A new technol

Updated on: September 23,2024

Closed-eye imaging can track wakefulness, awareness and pain in unresponsive conditions

byTel-Aviv UniversityPupillary light reflex (PLR) assessment in open-eye and closed-eye conditions. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00572-1A new technol

Updated on:September 23,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on: January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on:January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on: January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on:January 12,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on: June 14,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on:June 14,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on: February 18,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on:February 18,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on: March 28,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on:March 28,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on: February 21,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on:February 21,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024