Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

Senescent glial cell: A key player in lipid accumulation and brain aging

Updated on: October 21,2024

Senescent glial cell: A key player in lipid accumulation and brain aging

Updated on:October 21,2024

Research offers insight into future understanding of MS and its treatments

byTrinity College DublinComparison of EBNA-1 IgG Levels in Healthy Controls and People With MS and Epilepsy. Credit:Neurology Neuroimmunology & Neuroinflammation(2024). DOI: 10.1

Updated on: April 06,2024

Research offers insight into future understanding of MS and its treatments

byTrinity College DublinComparison of EBNA-1 IgG Levels in Healthy Controls and People With MS and Epilepsy. Credit:Neurology Neuroimmunology & Neuroinflammation(2024). DOI: 10.1

Updated on:April 06,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on: May 20,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on:May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on: May 05,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on:May 05,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Interferon drives cognitive impairment in Alzheimer's disease model

by Baylor College of MedicineCredit: CC0 Public DomainAlzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new thin

Updated on: June 04,2024

Interferon drives cognitive impairment in Alzheimer's disease model

by Baylor College of MedicineCredit: CC0 Public DomainAlzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new thin

Updated on:June 04,2024