Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on: June 11,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on:June 11,2024

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on: March 19,2024

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on:March 19,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on: February 03,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on:February 03,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on: May 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on:May 06,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on: September 23,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on:September 23,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Neural activity study shows the brain processes direct speech and its echo separately

byPublic Library of ScienceSpeech processing in an echoic environment. Credit: Jiaxin Gao (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Echoes can make speech harder to understand, and tuning

Updated on: March 13,2024

Neural activity study shows the brain processes direct speech and its echo separately

byPublic Library of ScienceSpeech processing in an echoic environment. Credit: Jiaxin Gao (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Echoes can make speech harder to understand, and tuning

Updated on:March 13,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on: June 14,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on:June 14,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on: March 19,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on:March 19,2024