Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024 16

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024 16

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024 3

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024 3

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on: March 02,2024 18

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on:March 02,2024 18

Unique visual stimulation may be new treatment for Alzheimer's

by Massachusetts Institute of TechnologyProfessor Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, and senior author of the study, which appears in the Dec. 7 online

Updated on: May 22,2024 5

Unique visual stimulation may be new treatment for Alzheimer's

by Massachusetts Institute of TechnologyProfessor Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, and senior author of the study, which appears in the Dec. 7 online

Updated on:May 22,2024 5

Study discovers possible tool to diagnose common contributor to vascular dementia

by Keck School of Medicine of USCOptical coherence tomography angiography (OCTA) images representative of high (top row), and low (bottom row) OCTA perfusion measures, and their corresponding FW

Updated on: March 02,2024 11

Study discovers possible tool to diagnose common contributor to vascular dementia

by Keck School of Medicine of USCOptical coherence tomography angiography (OCTA) images representative of high (top row), and low (bottom row) OCTA perfusion measures, and their corresponding FW

Updated on:March 02,2024 11

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024 7

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024 7

Scientists map the neural pathways for vomiting after eating infected food

by Cell PressCredit: Pixabay/CC0 Public DomainThe urge to vomit after eating contaminated food is the body's natural defensive response to get rid of bacterial toxins. However, the process of

Updated on: June 03,2024 3

Scientists map the neural pathways for vomiting after eating infected food

by Cell PressCredit: Pixabay/CC0 Public DomainThe urge to vomit after eating contaminated food is the body's natural defensive response to get rid of bacterial toxins. However, the process of

Updated on:June 03,2024 3

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024 15

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024 15

How a rare dementia transforms patients into artists

by Suzanne Leigh,University of California, San FranciscoArtwork from a patient with semantic variant primary progressive aphasia. Credit: University of California, San FranciscoFor decades, doct

Updated on: April 16,2024 14

How a rare dementia transforms patients into artists

by Suzanne Leigh,University of California, San FranciscoArtwork from a patient with semantic variant primary progressive aphasia. Credit: University of California, San FranciscoFor decades, doct

Updated on:April 16,2024 14

Docking peptides, slow to lock, open possible path to treat Alzheimer's

by Mike Williams,Rice UniversityUsing computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achil

Updated on: May 26,2024 4

Docking peptides, slow to lock, open possible path to treat Alzheimer's

by Mike Williams,Rice UniversityUsing computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achil

Updated on:May 26,2024 4

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024 9

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024 9

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024 5

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024 5