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Neurology
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Propionate is a key anaplerotic substrate in pyruvate dehydrogenase-deficient brain
Neurology
Propionate is a key anaplerotic substrate in pyruvate dehydrogenase-deficient brain
November 28,2024
Latest Articles
Adult-born dentate granule cells support the activity of hippocampal cell populations

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent
Updated on: February 05,2024
Adult-born dentate granule cells support the activity of hippocampal cell populations

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent
Updated on:February 05,2024
Dementia kills nearly three times more people than previously thought

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo
Updated on: May 06,2024
Dementia kills nearly three times more people than previously thought

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo
Updated on:May 06,2024
Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu
Updated on: June 11,2024
Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu
Updated on:June 11,2024
Fewer Asians, Blacks, Hispanics eligible for drugs that may delay Alzheimer's progression

Fewer Asians, Blacks, Hispanics eligible for drugs that may delay Alzheimer's progression

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainThe development of anti-amyloid monoclonal antibodies that may slow the progression of Alzheimer's disease by breaki
Updated on: June 05,2024
Fewer Asians, Blacks, Hispanics eligible for drugs that may delay Alzheimer's progression

Fewer Asians, Blacks, Hispanics eligible for drugs that may delay Alzheimer's progression

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainThe development of anti-amyloid monoclonal antibodies that may slow the progression of Alzheimer's disease by breaki
Updated on:June 05,2024
Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainWomen with diets during middle age designed to lower blood pressure were about 17% less likely to report memory loss and other signs of cogni
Updated on: February 24,2024
Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainWomen with diets during middle age designed to lower blood pressure were about 17% less likely to report memory loss and other signs of cogni
Updated on:February 24,2024
Research participation associated with greater adherence to medications for dementia, fewer racial disparities

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p
Updated on: May 05,2024
Research participation associated with greater adherence to medications for dementia, fewer racial disparities

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p
Updated on:May 05,2024
Breakthrough research reveals a new target for Alzheimer's disease treatment

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A
Updated on: February 26,2024
Breakthrough research reveals a new target for Alzheimer's disease treatment

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A
Updated on:February 26,2024
New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k
Updated on: March 28,2024
New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k
Updated on:March 28,2024
Halloween can be a scary time for people with dementia. Here's how to help

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved
Updated on: May 26,2024
Halloween can be a scary time for people with dementia. Here's how to help

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved
Updated on:May 26,2024
Single-cell dissection of Alzheimer's vascular changes across six brain regions

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD
Updated on: April 20,2024
Single-cell dissection of Alzheimer's vascular changes across six brain regions

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD
Updated on:April 20,2024
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