Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on: May 06,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on:May 06,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on: May 05,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on:May 05,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on: May 20,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on:May 20,2024

Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

by American Institute of PhysicsCredit: Unsplash/CC0 Public DomainCerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the

Updated on: February 03,2024

Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

by American Institute of PhysicsCredit: Unsplash/CC0 Public DomainCerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the

Updated on:February 03,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on: April 18,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on:April 18,2024