Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on: January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on:January 12,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on: May 05,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on:May 05,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on: January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on:January 10,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on: April 18,2024

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on:April 18,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on: May 06,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on:May 06,2024

Mouse study discovers specialized macrophages play key role in muscle movement

by Samantha Rey,Imperial College LondonMSMP activation or inhibition elicit rapid neural activity with muscle contraction or impair muscle activity in response to stretch, respectively. Credit:&

Updated on: December 17,2024

Mouse study discovers specialized macrophages play key role in muscle movement

by Samantha Rey,Imperial College LondonMSMP activation or inhibition elicit rapid neural activity with muscle contraction or impair muscle activity in response to stretch, respectively. Credit:&

Updated on:December 17,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Resolve to get a free memory screening in 2024

by Dennis ThompsonThere are so many New Year's resolutions from which to choose, but an important one could be to schedule a memory screening, experts say.Memory screenings consist of a series of

Updated on: January 09,2024

Resolve to get a free memory screening in 2024

by Dennis ThompsonThere are so many New Year's resolutions from which to choose, but an important one could be to schedule a memory screening, experts say.Memory screenings consist of a series of

Updated on:January 09,2024