No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on: April 29,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on:April 29,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on: May 20,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on:May 20,2024