Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024 10

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024 10

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024 5

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024 5

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on: February 03,2024 11

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on:February 03,2024 11

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on: February 03,2024 13

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on:February 03,2024 13

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on: June 15,2024 5

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on:June 15,2024 5

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024 0

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024 0

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024 20

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024 20

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024 6

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024 6

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on: February 26,2024 15

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on:February 26,2024 15

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on: March 19,2024 13

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on:March 19,2024 13

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024 13

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024 13

Important signs of blood clots in the lungs missed in patients with dementia

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainPatients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much les

Updated on: May 09,2024 8

Important signs of blood clots in the lungs missed in patients with dementia

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainPatients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much les

Updated on:May 09,2024 8