Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on: February 18,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on:February 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on: June 01,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on:June 01,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024