Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on: November 28,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on:November 28,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on: January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on:January 12,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on: February 21,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on:February 21,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on: March 28,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on:March 28,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on: February 24,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on:February 24,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on: February 18,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on:February 18,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024