'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on: May 26,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on:May 26,2024

Hippocampus uses dual pathways for memory storage

byRIKENOverview and motivation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44877-0The mechanism by which our brains record events in stereo—with one channel recordin

Updated on: July 05,2024

Hippocampus uses dual pathways for memory storage

byRIKENOverview and motivation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44877-0The mechanism by which our brains record events in stereo—with one channel recordin

Updated on:July 05,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on: January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on:January 10,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

DNA vaccine protects against toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterUT Southwestern researchers have developed a DNA vaccine that helps the body protect against toxic proteins associated with Alzheimer's disease. These images

Updated on: March 30,2024

DNA vaccine protects against toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterUT Southwestern researchers have developed a DNA vaccine that helps the body protect against toxic proteins associated with Alzheimer's disease. These images

Updated on:March 30,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024