Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024 18

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024 18

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on: June 15,2024 5

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on:June 15,2024 5

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on: March 19,2024 12

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on:March 19,2024 12

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024 12

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024 12

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on: April 20,2024 0

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on:April 20,2024 0

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on: November 07,2024 0

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on:November 07,2024 0

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024 3

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024 3

Study suggests marijuana use damages brain immune cells vital to adolescent development

byJohns Hopkins University School of MedicineCnr1 expression in the microglia of the mouse brain.aExperimental flow of Fluorescence-Activated Cell Sorting (FACS)-based microglia (CD4

Updated on: January 12,2024 17

Study suggests marijuana use damages brain immune cells vital to adolescent development

byJohns Hopkins University School of MedicineCnr1 expression in the microglia of the mouse brain.aExperimental flow of Fluorescence-Activated Cell Sorting (FACS)-based microglia (CD4

Updated on:January 12,2024 17

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024 5

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024 5

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on: January 12,2024 16

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on:January 12,2024 16

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024 13

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024 13

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on: February 03,2024 13

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on:February 03,2024 13