Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on: October 28,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on:October 28,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on: March 20,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on:March 20,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on: June 05,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on:June 05,2024