New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024

New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on: June 15,2024

New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on:June 15,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on: June 11,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on:June 11,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on: January 21,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on:January 21,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on: April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on:April 29,2024

Mouse study discovers specialized macrophages play key role in muscle movement

by Samantha Rey,Imperial College LondonMSMP activation or inhibition elicit rapid neural activity with muscle contraction or impair muscle activity in response to stretch, respectively. Credit:&

Updated on: December 17,2024

Mouse study discovers specialized macrophages play key role in muscle movement

by Samantha Rey,Imperial College LondonMSMP activation or inhibition elicit rapid neural activity with muscle contraction or impair muscle activity in response to stretch, respectively. Credit:&

Updated on:December 17,2024