Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on: March 20,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on:March 20,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on: April 02,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on:April 02,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on: January 11,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on:January 11,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on: October 28,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on:October 28,2024