Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on: February 03,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on:February 03,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on: April 25,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on:April 25,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on: January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on:January 10,2024

Study identifies new biomarkers of Alzheimer's disease

by Ingrid Fadelli , Medical XpressStudy overview. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01924-6Recent advances in the study of proteomes (i.e., the entire range of p

Updated on: July 31,2024

Study identifies new biomarkers of Alzheimer's disease

by Ingrid Fadelli , Medical XpressStudy overview. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01924-6Recent advances in the study of proteomes (i.e., the entire range of p

Updated on:July 31,2024

Leading AI chatbots show dementia-like cognitive decline in tests, raising questions about their future in medicine

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainAlmost all leading large language models or "chatbots" show signs of mild cognitive impairment in tests widely used to spot ea

Updated on: January 18,2025

Leading AI chatbots show dementia-like cognitive decline in tests, raising questions about their future in medicine

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainAlmost all leading large language models or "chatbots" show signs of mild cognitive impairment in tests widely used to spot ea

Updated on:January 18,2025

More parents are delaying their kids' vaccines, and it's alarming pediatricians

by Jenny Gold, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs measles cases pop up across the country this winter—including several in California—one group of children is stirring deep concerns

Updated on: March 19,2024

More parents are delaying their kids' vaccines, and it's alarming pediatricians

by Jenny Gold, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs measles cases pop up across the country this winter—including several in California—one group of children is stirring deep concerns

Updated on:March 19,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on: September 23,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on:September 23,2024