Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on: January 11,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on:January 11,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on: March 30,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on:March 30,2024

Neuroscientists uncover therapeutic potential of low-dose ionizing radiation for traumatic brain injury, ischemic stroke

JANUARY 26, 2024 Editors' notesbyCity University of Hong KongLDIR treatment induces axonal sprouting, brain rewiring and EEG oscillatory activity two months after ischemic stroke. (A) In X-r

Updated on: March 13,2024

Neuroscientists uncover therapeutic potential of low-dose ionizing radiation for traumatic brain injury, ischemic stroke

JANUARY 26, 2024 Editors' notesbyCity University of Hong KongLDIR treatment induces axonal sprouting, brain rewiring and EEG oscillatory activity two months after ischemic stroke. (A) In X-r

Updated on:March 13,2024

New approach to traumatic brain injuries could revolutionise diagnosis and treatment

by Queen Mary, University of LondonFigure 1. Cerebral biopsy sample and fluorescent immunostaining. (A) An image of the cerebral biopsy obtained from a severe TBI patient and fixed in 10% formali

Updated on: February 03,2024

New approach to traumatic brain injuries could revolutionise diagnosis and treatment

by Queen Mary, University of LondonFigure 1. Cerebral biopsy sample and fluorescent immunostaining. (A) An image of the cerebral biopsy obtained from a severe TBI patient and fixed in 10% formali

Updated on:February 03,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on: January 10,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on:January 10,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on: February 05,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on:February 05,2024