Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on: February 03,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on:February 03,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on: April 25,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on:April 25,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

How do we get more women into health care and medical leadership?

by Medical Journal of Australia (MJA)Credit: National Cancer Institute on UnsplashWomen continue to be under-represented in health care and medical leadership in Australia, with experts labeling the d

Updated on: March 19,2024

How do we get more women into health care and medical leadership?

by Medical Journal of Australia (MJA)Credit: National Cancer Institute on UnsplashWomen continue to be under-represented in health care and medical leadership in Australia, with experts labeling the d

Updated on:March 19,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on: January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on:January 10,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on: March 15,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on:March 15,2024

More parents are delaying their kids' vaccines, and it's alarming pediatricians

by Jenny Gold, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs measles cases pop up across the country this winter—including several in California—one group of children is stirring deep concerns

Updated on: March 19,2024

More parents are delaying their kids' vaccines, and it's alarming pediatricians

by Jenny Gold, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs measles cases pop up across the country this winter—including several in California—one group of children is stirring deep concerns

Updated on:March 19,2024