'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

Brain flexibility may hasten hearing improvements from cochlear implants

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainKickstarting the brain's natural ability to adjust to new circumstances, or neuroplasticity, improves how effectively a cochlear implant

Updated on: February 21,2024

Brain flexibility may hasten hearing improvements from cochlear implants

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainKickstarting the brain's natural ability to adjust to new circumstances, or neuroplasticity, improves how effectively a cochlear implant

Updated on:February 21,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on: March 26,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on:March 26,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Smarter CT scans may approach the level of MRI and support dementia diagnosis

by Margareta G. Kubista,Swedish Research CouncilImaging-based volumetric measures. The CT-based GM, WM, CSF, ICV and VCSF maps were automatically segmented using deep-learning techniques. Credit

Updated on: March 02,2024

Smarter CT scans may approach the level of MRI and support dementia diagnosis

by Margareta G. Kubista,Swedish Research CouncilImaging-based volumetric measures. The CT-based GM, WM, CSF, ICV and VCSF maps were automatically segmented using deep-learning techniques. Credit

Updated on:March 02,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on: February 24,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on:February 24,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on: June 14,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on:June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on: April 22,2024

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on:April 22,2024