Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on: March 19,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on:March 19,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on: February 03,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on:February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Brain plasticity study: Oxytocin drives development of neural connections in adult-born neurons

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainLearning a new task, mastering a musical instrument or being able to adapt to the constantly changing environment are all possible th

Updated on: February 21,2024

Brain plasticity study: Oxytocin drives development of neural connections in adult-born neurons

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainLearning a new task, mastering a musical instrument or being able to adapt to the constantly changing environment are all possible th

Updated on:February 21,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on: May 21,2024

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on:May 21,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024