New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on: February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on:February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

What happens to your brain as you age

Updated on: August 15,2024

What happens to your brain as you age

Updated on:August 15,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on: February 26,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on:February 26,2024

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on: April 18,2024

How toxic protein spreads in Alzheimer's disease

by Lund UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Toxic versions of the protein tau are believed to cause death of neurons of the br

Updated on:April 18,2024

Researchers map the entire brain of an adult fruit fly for the first time

byPrinceton UniversityThis map shows the precise location and arrangement of the 50 largest neurons of the fly brain connectome. These 50, along with another 139,205 brain cells in the brain of

Updated on: October 18,2024

Researchers map the entire brain of an adult fruit fly for the first time

byPrinceton UniversityThis map shows the precise location and arrangement of the 50 largest neurons of the fly brain connectome. These 50, along with another 139,205 brain cells in the brain of

Updated on:October 18,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

FDA approves first drug meant to ease Alzheimer's-linked agitation

by Cara MurezA medication to treat agitation in Alzheimer's patients now has approval from the U.S. Food and Drug Administration.The FDA gave supplemental approval to Otsuka Pharmaceutical Company

Updated on: March 30,2024

FDA approves first drug meant to ease Alzheimer's-linked agitation

by Cara MurezA medication to treat agitation in Alzheimer's patients now has approval from the U.S. Food and Drug Administration.The FDA gave supplemental approval to Otsuka Pharmaceutical Company

Updated on:March 30,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on: May 22,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on:May 22,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on: February 24,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on:February 24,2024