Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

A new book by neuroscientist offers strategies for reducing the risk of Alzheimer's disease

by Julie Cohen,University of California - Santa BarbaraA brain illustration. Credit: UCSBDiet, exercise, a good night's sleep—all sound recommendations for mitigating one's risk for ever

Updated on: February 27,2024

A new book by neuroscientist offers strategies for reducing the risk of Alzheimer's disease

by Julie Cohen,University of California - Santa BarbaraA brain illustration. Credit: UCSBDiet, exercise, a good night's sleep—all sound recommendations for mitigating one's risk for ever

Updated on:February 27,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on: February 05,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on:February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Researchers find regional variations in concussion diagnoses

by Marco Schimizzi,Michigan State UniversityCredit: AI-generated imageResearchers in Michigan State University's Department of Kinesiology found significant geographic variations in concussi

Updated on: September 03,2024

Researchers find regional variations in concussion diagnoses

by Marco Schimizzi,Michigan State UniversityCredit: AI-generated imageResearchers in Michigan State University's Department of Kinesiology found significant geographic variations in concussi

Updated on:September 03,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on: May 22,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on:May 22,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

Comparative Efficacy of Tenecteplase versus Alteplase in Thrombolytic Treatment of Acute Ischemic Stroke

Updated on: February 20,2024

Comparative Efficacy of Tenecteplase versus Alteplase in Thrombolytic Treatment of Acute Ischemic Stroke

Updated on:February 20,2024