Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on: February 21,2024

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on:February 21,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on: February 18,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on:February 18,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on: February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on:February 05,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024