Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on: July 08,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on:July 08,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on: March 28,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on:March 28,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on: April 20,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on:April 20,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on: March 05,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on:March 05,2024