Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on: June 01,2024

Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on:June 01,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on: April 20,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on:April 20,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on: March 28,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on:March 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on: April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on:April 28,2024