Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on: September 23,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on:September 23,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on: July 31,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on:July 31,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on: May 13,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on:May 13,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on: April 29,2024

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on:April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on: April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on:April 29,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on: April 28,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on:April 28,2024