A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on: June 05,2024

A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on:June 05,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024

Personal wealth associated with health care costs in people with Alzheimer's disease

by University of Eastern FinlandCredit: Pixabay/CC0 Public DomainFinland has a strong public health care system; nevertheless, personal wealth is associated with the costs of hospital care and me

Updated on: February 24,2024

Personal wealth associated with health care costs in people with Alzheimer's disease

by University of Eastern FinlandCredit: Pixabay/CC0 Public DomainFinland has a strong public health care system; nevertheless, personal wealth is associated with the costs of hospital care and me

Updated on:February 24,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on: February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on:February 05,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on: April 02,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on:April 02,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024