Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on: June 01,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on:June 01,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Global experts seek to end damaging dementia psychosis cycle

by University of ExeterAntisychotics can be damaging in dementia. Credit: University of ExeterA new research report calls for a change in approach in the treatment of psychosis in dementia, to fi

Updated on: March 09,2024

Global experts seek to end damaging dementia psychosis cycle

by University of ExeterAntisychotics can be damaging in dementia. Credit: University of ExeterA new research report calls for a change in approach in the treatment of psychosis in dementia, to fi

Updated on:March 09,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on: June 14,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on:June 14,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on: April 16,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on:April 16,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

Study maps brain wave disruptions affecting memory recall

by UT Southwestern Medical CenterTheta oscillations—brain waves associated with encoding memories—lessen in intensity with administration of a drug called scopolamine, according to a study by UT

Updated on: March 02,2024

Study maps brain wave disruptions affecting memory recall

by UT Southwestern Medical CenterTheta oscillations—brain waves associated with encoding memories—lessen in intensity with administration of a drug called scopolamine, according to a study by UT

Updated on:March 02,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on: February 03,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on:February 03,2024