How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

Computer avatars play a part in dementia detection

by Osaka UniversityFigure 1. Human-Avatar Dialogue System. Figure 1. Human-Avatar Dialogue System: (a)Introduction “What’s your name?”(b) Gaze measurement(c) Reading test(d) Fixed question “What’

Updated on: May 22,2024

Computer avatars play a part in dementia detection

by Osaka UniversityFigure 1. Human-Avatar Dialogue System. Figure 1. Human-Avatar Dialogue System: (a)Introduction “What’s your name?”(b) Gaze measurement(c) Reading test(d) Fixed question “What’

Updated on:May 22,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on: April 25,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on:April 25,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on: July 31,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on:July 31,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on: January 21,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on:January 21,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on: November 28,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on:November 28,2024

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Updated on: June 18,2024

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Updated on:June 18,2024