How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on: January 21,2024

COVID-19 lockdowns linked to less accurate recollection of event timing

byPublic Library of ScienceSimilar to a landscape where objects/people are placed in relation to others, a timescape puts the event timeline in relation to other events. Credit: Arianna Sahraie

Updated on:January 21,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Comparative Efficacy of Tenecteplase versus Alteplase in Thrombolytic Treatment of Acute Ischemic Stroke

Updated on: February 20,2024

Comparative Efficacy of Tenecteplase versus Alteplase in Thrombolytic Treatment of Acute Ischemic Stroke

Updated on:February 20,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on: April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on:April 29,2024

Need for formal bereavement support in dementia care is largely underestimated

by University College LondonCredit: Unsplash/CC0 Public DomainThe need for grief counseling in dementia care may be substantially underestimated, according to new research led by a UCL academic.T

Updated on: May 08,2024

Need for formal bereavement support in dementia care is largely underestimated

by University College LondonCredit: Unsplash/CC0 Public DomainThe need for grief counseling in dementia care may be substantially underestimated, according to new research led by a UCL academic.T

Updated on:May 08,2024

Thinking 'out-of-the-box' may build a better brain and prevent dementia

by Florida Atlantic UniversityFAU Neuroscientist James Galvin, M.D., uses the functional range of motion board to test a patient's manual dexterity as part of the Dementia Prevention Initiati

Updated on: March 13,2024

Thinking 'out-of-the-box' may build a better brain and prevent dementia

by Florida Atlantic UniversityFAU Neuroscientist James Galvin, M.D., uses the functional range of motion board to test a patient's manual dexterity as part of the Dementia Prevention Initiati

Updated on:March 13,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on: September 23,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on:September 23,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on: April 25,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on:April 25,2024