A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on: February 24,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on:February 24,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024

Brain plasticity study: Oxytocin drives development of neural connections in adult-born neurons

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainLearning a new task, mastering a musical instrument or being able to adapt to the constantly changing environment are all possible th

Updated on: February 21,2024

Brain plasticity study: Oxytocin drives development of neural connections in adult-born neurons

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainLearning a new task, mastering a musical instrument or being able to adapt to the constantly changing environment are all possible th

Updated on:February 21,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on: June 01,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on:June 01,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on: February 27,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on:February 27,2024

A new book by neuroscientist offers strategies for reducing the risk of Alzheimer's disease

by Julie Cohen,University of California - Santa BarbaraA brain illustration. Credit: UCSBDiet, exercise, a good night's sleep—all sound recommendations for mitigating one's risk for ever

Updated on: February 27,2024

A new book by neuroscientist offers strategies for reducing the risk of Alzheimer's disease

by Julie Cohen,University of California - Santa BarbaraA brain illustration. Credit: UCSBDiet, exercise, a good night's sleep—all sound recommendations for mitigating one's risk for ever

Updated on:February 27,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on: April 20,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on:April 20,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on: March 28,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on:March 28,2024