A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Study discovers a 'brain thesaurus' that lets neurons derive meaning from spoken words

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainUsing a novel technology for obtaining recordings from single neurons, a team of investigators at Massachusetts General Ho

Updated on: July 05,2024

Study discovers a 'brain thesaurus' that lets neurons derive meaning from spoken words

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainUsing a novel technology for obtaining recordings from single neurons, a team of investigators at Massachusetts General Ho

Updated on:July 05,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on: April 02,2024

Alzheimer's, related disorders and language: How we talk about 'dementia' is key to building community bridges

by Arnaud Francioni, Melissa Park, Patricia Belchior, Thomas Valente,The ConversationCredit: Pixabay/CC0 Public DomainPeople living withAlzheimer's diseaseand other related disor

Updated on:April 02,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on: February 18,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on:February 18,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on: October 16,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on:October 16,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

How near-death experiences and psychedelics alter attitudes about death

by Public Library of ScienceAn image of a tunnel in Duluth, Minnesota, reminiscent of classic Near Death Experience features (a bright light at the end of a tunnel at a point of no return). Credi

Updated on: February 05,2024

How near-death experiences and psychedelics alter attitudes about death

by Public Library of ScienceAn image of a tunnel in Duluth, Minnesota, reminiscent of classic Near Death Experience features (a bright light at the end of a tunnel at a point of no return). Credi

Updated on:February 05,2024

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on: February 21,2024

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on:February 21,2024