'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on: May 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on:May 06,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on: May 20,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on:May 20,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on: October 16,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on:October 16,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on: February 21,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on:February 21,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on: July 01,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on:July 01,2024

Hourly heat exposure linked to increased risk for acute ischemic stroke

by Elana GotkineHourly heat exposure is associated with an increased risk for acute ischemic stroke (AIS) onset, according to a study published online Feb. 28 inJAMA Network Open.Xinlei Zhu, fro

Updated on: March 15,2024

Hourly heat exposure linked to increased risk for acute ischemic stroke

by Elana GotkineHourly heat exposure is associated with an increased risk for acute ischemic stroke (AIS) onset, according to a study published online Feb. 28 inJAMA Network Open.Xinlei Zhu, fro

Updated on:March 15,2024

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on: June 01,2024

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on:June 01,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on: February 27,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on:February 27,2024