Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Cure for male pattern baldness given boost by sugar discovery

byUniversity of SheffieldMicroscopic analysis of skin sections retrieved on day 21 of experiment after H&E staining. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.20

Updated on: August 01,2024

Cure for male pattern baldness given boost by sugar discovery

byUniversity of SheffieldMicroscopic analysis of skin sections retrieved on day 21 of experiment after H&E staining. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.20

Updated on:August 01,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on: February 03,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on:February 03,2024

Traumatic brain injury may raise veterans' long-term stroke risk

by Michael Merschel, American Heart Association NewsMilitary veterans who had a traumatic brain injury may have an increased long-term risk of stroke, new research suggests.The study, which used data

Updated on: February 03,2024

Traumatic brain injury may raise veterans' long-term stroke risk

by Michael Merschel, American Heart Association NewsMilitary veterans who had a traumatic brain injury may have an increased long-term risk of stroke, new research suggests.The study, which used data

Updated on:February 03,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on: January 12,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on:January 12,2024

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on: April 08,2024

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on:April 08,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on: June 11,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on:June 11,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on: April 06,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on:April 06,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on: March 19,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on:March 19,2024