FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on: April 20,2024

Major step towards Alzheimer's blood test

by Cardiff UniversityCredit: Cardiff UniversityA research team, led by Cardiff University, has made a significant step towards the development of a simple blood test to predict the onset of Alzhe

Updated on:April 20,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on: May 18,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on:May 18,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on: March 30,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on:March 30,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024