Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on: July 08,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on:July 08,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on: May 17,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on:May 17,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on: May 18,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on:May 18,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on: May 22,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on:May 22,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on: February 05,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on:February 05,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024