A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on: May 20,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on:May 20,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on: May 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on:May 06,2024

MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on: March 30,2024

MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on:March 30,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on: June 14,2024

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on:June 14,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on: April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on:April 20,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on: April 08,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on:April 08,2024

New research finds a direct communication path between the lungs and the brain

byUniversity of CalgaryCredit:Cell(2024). DOI: 10.1016/j.cell.2024.03.001University of Calgary researchers have discovered the lungs communicate directly with the brain when there is

Updated on: March 28,2024

New research finds a direct communication path between the lungs and the brain

byUniversity of CalgaryCredit:Cell(2024). DOI: 10.1016/j.cell.2024.03.001University of Calgary researchers have discovered the lungs communicate directly with the brain when there is

Updated on:March 28,2024