Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on: July 08,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on:July 08,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on: February 05,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on:February 05,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on: May 17,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on:May 17,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024