Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on: April 28,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on:April 28,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on: April 06,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on:April 06,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on: June 14,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on:June 14,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on: June 24,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on:June 24,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on: June 11,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on:June 11,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on: April 16,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on:April 16,2024

Adults with Alzheimer's risk factors show subtle alterations in brain networks despite normal cognition

by Jason Clement,McGill UniversityPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at McGill University and the Douglas Mental Health University Institute

Updated on: June 07,2024

Adults with Alzheimer's risk factors show subtle alterations in brain networks despite normal cognition

by Jason Clement,McGill UniversityPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at McGill University and the Douglas Mental Health University Institute

Updated on:June 07,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024