Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on: May 13,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on:May 13,2024

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on: April 22,2024

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on:April 22,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on: April 16,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on:April 16,2024

Magnetic resonance imaging shows brain inflammation in vivo for the first time

by Spanish National Research Council (CSIC)Researchers from the UMH-CSIC Neurosciences Institute have developed an innovative strategy that allows imaging of microglial and astrocyte activation in the

Updated on: February 05,2024

Magnetic resonance imaging shows brain inflammation in vivo for the first time

by Spanish National Research Council (CSIC)Researchers from the UMH-CSIC Neurosciences Institute have developed an innovative strategy that allows imaging of microglial and astrocyte activation in the

Updated on:February 05,2024

Cancer chemotherapy drug reverses Alzheimer's symptoms in mice

by University of British ColumbiaCredit: Pixabay/CC0 Public DomainA drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's d

Updated on: April 25,2024

Cancer chemotherapy drug reverses Alzheimer's symptoms in mice

by University of British ColumbiaCredit: Pixabay/CC0 Public DomainA drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's d

Updated on:April 25,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on: June 11,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on:June 11,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

New study shows exercise can boost brain health

by IOS PressCredit: CC0 Public DomainA fascinating link between regular exercise and better brain health has been revealed, according to an international study that included a team of clinical re

Updated on: February 24,2024

New study shows exercise can boost brain health

by IOS PressCredit: CC0 Public DomainA fascinating link between regular exercise and better brain health has been revealed, according to an international study that included a team of clinical re

Updated on:February 24,2024