How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on: January 12,2024

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on:January 12,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on: April 06,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on:April 06,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on: March 30,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on:March 30,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on: June 05,2024

A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on:June 05,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Synapse discovery could lead to new treatments for Alzheimer's disease

by University of New South WalesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A team of researchers led by UNSW Australia scientists has discovere

Updated on: February 27,2024

Synapse discovery could lead to new treatments for Alzheimer's disease

by University of New South WalesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A team of researchers led by UNSW Australia scientists has discovere

Updated on:February 27,2024

Neuroscientists uncover therapeutic potential of low-dose ionizing radiation for traumatic brain injury, ischemic stroke

JANUARY 26, 2024 Editors' notesbyCity University of Hong KongLDIR treatment induces axonal sprouting, brain rewiring and EEG oscillatory activity two months after ischemic stroke. (A) In X-r

Updated on: March 13,2024

Neuroscientists uncover therapeutic potential of low-dose ionizing radiation for traumatic brain injury, ischemic stroke

JANUARY 26, 2024 Editors' notesbyCity University of Hong KongLDIR treatment induces axonal sprouting, brain rewiring and EEG oscillatory activity two months after ischemic stroke. (A) In X-r

Updated on:March 13,2024