How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on: February 27,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on:February 27,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on: May 20,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on:May 20,2024

Brain 'fingerprinting' provides insights into mental health of young adolescents

by University of the Sunshine CoastCredit: Unsplash/CC0 Public DomainMedical imaging of a person's unique brain signature—much like a fingerprint—has the potential to predict mental health problem

Updated on: February 18,2024

Brain 'fingerprinting' provides insights into mental health of young adolescents

by University of the Sunshine CoastCredit: Unsplash/CC0 Public DomainMedical imaging of a person's unique brain signature—much like a fingerprint—has the potential to predict mental health problem

Updated on:February 18,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on: June 11,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on:June 11,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Novel algorithm improves intracranial EEG accuracy to enhance future patient care

byUniversity of Minnesota Medical SchoolThe ABCD Algorithm. (A) Example raw log-power spectra from 152 channels during a single recording session. (B) Example, mean log-power spectrum and second

Updated on: September 06,2024

Novel algorithm improves intracranial EEG accuracy to enhance future patient care

byUniversity of Minnesota Medical SchoolThe ABCD Algorithm. (A) Example raw log-power spectra from 152 channels during a single recording session. (B) Example, mean log-power spectrum and second

Updated on:September 06,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Alzheimer's gene-mapping project proposed in New York state

A proposed project to map the genes of 1 million people in New York living with or at risk for Alzheimer disease was announced Friday by Gov. Andrew Cuomo.He said the five years of data collected by t

Updated on: April 20,2024

Alzheimer's gene-mapping project proposed in New York state

A proposed project to map the genes of 1 million people in New York living with or at risk for Alzheimer disease was announced Friday by Gov. Andrew Cuomo.He said the five years of data collected by t

Updated on:April 20,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on: June 24,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on:June 24,2024

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on: January 12,2024

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on:January 12,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on: April 25,2024

Alzheimer's linked to the brain's 'garbage disposal service'

by Andrew Spence, The LeadPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers in South Australia have found a genetic link between Alzheimer's disease and the

Updated on:April 25,2024