In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on: April 23,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on:April 23,2024

Blood-based marker for Alzheimer's disease shows diagnostic potential

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers in Japan and Australia have used the ratio of different fo

Updated on: April 08,2024

Blood-based marker for Alzheimer's disease shows diagnostic potential

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers in Japan and Australia have used the ratio of different fo

Updated on:April 08,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Brain 'fingerprinting' provides insights into mental health of young adolescents

by University of the Sunshine CoastCredit: Unsplash/CC0 Public DomainMedical imaging of a person's unique brain signature—much like a fingerprint—has the potential to predict mental health problem

Updated on: February 18,2024

Brain 'fingerprinting' provides insights into mental health of young adolescents

by University of the Sunshine CoastCredit: Unsplash/CC0 Public DomainMedical imaging of a person's unique brain signature—much like a fingerprint—has the potential to predict mental health problem

Updated on:February 18,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on: March 30,2024

MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on:March 30,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on: April 28,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on:April 28,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024