MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on: March 30,2024

MRI method purported to detect neurons' rapid impulses produces its own misleading signals instead

by McGovern Institute for Brain ResearchCredit: Pixabay/CC0 Public DomainA new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally rep

Updated on:March 30,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on: June 11,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on:June 11,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on: May 18,2024

How a protein in your brain could protect against Alzheimer's disease

by Katie Willis,University of AlbertaCredit: CC0 Public DomainNew research has found that the most common version of a protein called CD33 plays a crucial role in regulating white blood cells in

Updated on:May 18,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on: April 06,2024

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on:April 06,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on: April 06,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on:April 06,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

3D imaging helps to better understand the early stages of Alzheimer's disease

by Karolinska InstitutetNoradrenergic neurons of the human locus coeruleus shell in three dimension. Credit: Gilvesy et al.Using a novel 3D imaging technology, researchers at Karolinska Institute

Updated on: March 13,2024

3D imaging helps to better understand the early stages of Alzheimer's disease

by Karolinska InstitutetNoradrenergic neurons of the human locus coeruleus shell in three dimension. Credit: Gilvesy et al.Using a novel 3D imaging technology, researchers at Karolinska Institute

Updated on:March 13,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on: May 20,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on:May 20,2024

Gene yields insights into the causes of neurodegeneration

by Cornell UniversityCredit: CC0 Public DomainAcross the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal

Updated on: June 14,2024

Gene yields insights into the causes of neurodegeneration

by Cornell UniversityCredit: CC0 Public DomainAcross the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal

Updated on:June 14,2024