Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

How the gut communicates with the brain

by Flinders UniversityCredit: PixabayHow the 'second brain' – the enteric nervous system in our gut—communicates with our first brain has been one of the most challenging questions faced

Updated on: February 03,2024

How the gut communicates with the brain

by Flinders UniversityCredit: PixabayHow the 'second brain' – the enteric nervous system in our gut—communicates with our first brain has been one of the most challenging questions faced

Updated on:February 03,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on: May 20,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on:May 20,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on: June 14,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on:June 14,2024

'Not enough therapists': Georgia lawmakers aim to support mental health workforce

by Michelle Baruchman, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainDuring the COVID-19 pandemic, more than 1,200 state psychiatric hospital employees left their positions, and jus

Updated on: March 19,2024

'Not enough therapists': Georgia lawmakers aim to support mental health workforce

by Michelle Baruchman, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainDuring the COVID-19 pandemic, more than 1,200 state psychiatric hospital employees left their positions, and jus

Updated on:March 19,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on: August 31,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on:August 31,2024

How our brain deconstructs a world in constant motion

by Isabella Kjaerulff, Duke Research BlogWas it a stop sign? I didn’t notice. Credit: US Marine Corps, via Wikimedia CommonsIt's a miracle that people aren't constantly getting into car accide

Updated on: January 12,2024

How our brain deconstructs a world in constant motion

by Isabella Kjaerulff, Duke Research BlogWas it a stop sign? I didn’t notice. Credit: US Marine Corps, via Wikimedia CommonsIt's a miracle that people aren't constantly getting into car accide

Updated on:January 12,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024