How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Breaking stereotype: Brain models are not one-size-fits-all

by Yale UniversityCredit: Pixabay/CC0 Public DomainMachine learning has helped scientists understand how the brain gives rise to complex human characteristics, uncovering patterns of brain activi

Updated on: February 18,2024

Breaking stereotype: Brain models are not one-size-fits-all

by Yale UniversityCredit: Pixabay/CC0 Public DomainMachine learning has helped scientists understand how the brain gives rise to complex human characteristics, uncovering patterns of brain activi

Updated on:February 18,2024

Discovery of macrophages' protective role for nerve damage opens new treatment path

Updated on: March 05,2025

Discovery of macrophages' protective role for nerve damage opens new treatment path

Updated on:March 05,2025

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Brain differences suggest that children and adults use different strategies to understand social interactions

by Bangor UniversityCredit: Unsplash/CC0 Public DomainUnderstanding the meaning of social interactions is an important human ability that relies on deciphering different kinds of social informati

Updated on: February 21,2024

Brain differences suggest that children and adults use different strategies to understand social interactions

by Bangor UniversityCredit: Unsplash/CC0 Public DomainUnderstanding the meaning of social interactions is an important human ability that relies on deciphering different kinds of social informati

Updated on:February 21,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on: April 18,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on:April 18,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on: May 17,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on:May 17,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on: February 03,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on:February 03,2024