Disrupted circadian regulation of cognition in Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityCredit: AI-generated imageCircadian dysfunction linked to Alzheimer's disease is known to disrupt sleep and daily activity patterns. New research i

Updated on: April 18,2024 12

Disrupted circadian regulation of cognition in Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityCredit: AI-generated imageCircadian dysfunction linked to Alzheimer's disease is known to disrupt sleep and daily activity patterns. New research i

Updated on:April 18,2024 12

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on: April 18,2024 11

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on:April 18,2024 11

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024 19

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024 19

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024 8

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024 8

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024 3

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024 3

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024 8

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024 8

Alzheimer's study: Electrostimulation to evoke vivid memories

by Wissam Deeb,The ConversationThe fornix, a tiny part of the brain, may hold some clues to memory loss. Credit: Wissam Deeb, CC BY-SAAlzheimer's diseaseis one of the most dreaded diag

Updated on: April 20,2024 17

Alzheimer's study: Electrostimulation to evoke vivid memories

by Wissam Deeb,The ConversationThe fornix, a tiny part of the brain, may hold some clues to memory loss. Credit: Wissam Deeb, CC BY-SAAlzheimer's diseaseis one of the most dreaded diag

Updated on:April 20,2024 17

Wrist device that monitors activity could help provide early warning of Alzheimer's

by Johns Hopkins University Bloomberg School of Public HealthGraphical Abstract. Credit:SLEEP(2024). DOI: 10.1093/sleep/zsae037Monitoring daily activity patterns using a wrist-worn de

Updated on: March 19,2024 12

Wrist device that monitors activity could help provide early warning of Alzheimer's

by Johns Hopkins University Bloomberg School of Public HealthGraphical Abstract. Credit:SLEEP(2024). DOI: 10.1093/sleep/zsae037Monitoring daily activity patterns using a wrist-worn de

Updated on:March 19,2024 12

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on: April 29,2024 14

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on:April 29,2024 14

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on: April 08,2024 10

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on:April 08,2024 10

Strategies and milestones for Alzheimer's patient and caregiver support outlined

by Indiana UniversityThe National Alzheimer's Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan's biomedical resear

Updated on: February 28,2024 10

Strategies and milestones for Alzheimer's patient and caregiver support outlined

by Indiana UniversityThe National Alzheimer's Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan's biomedical resear

Updated on:February 28,2024 10

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024 16

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024 16