Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on: March 30,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on:March 30,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

by American Institute of PhysicsCredit: Unsplash/CC0 Public DomainCerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the

Updated on: February 03,2024

Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

by American Institute of PhysicsCredit: Unsplash/CC0 Public DomainCerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the

Updated on:February 03,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on: June 01,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on:June 01,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on: April 23,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on:April 23,2024

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on: January 18,2025

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on:January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on: January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on:January 18,2025

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on: July 01,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on:July 01,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on: August 08,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on:August 08,2024

Better country dementia care

by Flinders UniversityCredit: CC0 Public DomainRising levels of dementia is putting pressure on residential aged care facilities, including in rural and regional centers where nursing homes and s

Updated on: June 05,2024

Better country dementia care

by Flinders UniversityCredit: CC0 Public DomainRising levels of dementia is putting pressure on residential aged care facilities, including in rural and regional centers where nursing homes and s

Updated on:June 05,2024