Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on: June 01,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on:June 01,2024

Eli Lilly hopeful of Alzheimer's drug approval after promising results

Credit: Unsplash/CC0 Public DomainA second Alzheimer's drug proven to slow cognitive decline was a step closer to US approval on Monday after clinical trial results published in a top journal conf

Updated on: March 09,2024

Eli Lilly hopeful of Alzheimer's drug approval after promising results

Credit: Unsplash/CC0 Public DomainA second Alzheimer's drug proven to slow cognitive decline was a step closer to US approval on Monday after clinical trial results published in a top journal conf

Updated on:March 09,2024

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on: January 12,2024

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on:January 12,2024

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on: January 12,2024

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on:January 12,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on: March 25,2024

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on:March 25,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on: March 19,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on:March 19,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on: June 11,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on:June 11,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024