Neuroprotective mechanism altered by Alzheimer's disease risk genes

by Molly Chiu,Baylor College of MedicineCredit: Baylor College of MedicineThe brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medic

Updated on: April 08,2024

Neuroprotective mechanism altered by Alzheimer's disease risk genes

by Molly Chiu,Baylor College of MedicineCredit: Baylor College of MedicineThe brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medic

Updated on:April 08,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on: March 02,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on:March 02,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on: February 05,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on:February 05,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on: September 23,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on:September 23,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on: March 19,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on:March 19,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on: February 26,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on:February 26,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on: December 17,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on:December 17,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024