Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

Global study could change how children with multiple sclerosis are treated

by Melbourne HealthCredit: CC0 Public DomainA new study—the largest of its kind globally—has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-ef

Updated on: March 28,2024

Global study could change how children with multiple sclerosis are treated

by Melbourne HealthCredit: CC0 Public DomainA new study—the largest of its kind globally—has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-ef

Updated on:March 28,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on: February 05,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on:February 05,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on: April 07,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on:April 07,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024

Race of people given Alzheimer's blood tests may affect interpretation of results

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainThree experimental blood tests used to identify people in early stages of Alzheimer's disease perform differently

Updated on: June 24,2024

Race of people given Alzheimer's blood tests may affect interpretation of results

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainThree experimental blood tests used to identify people in early stages of Alzheimer's disease perform differently

Updated on:June 24,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on: October 14,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on:October 14,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on: February 26,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on:February 26,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on: October 16,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on:October 16,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024