New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Researchers find that youthful proteins help nerves regrow

by Kim Krieger,University of ConnecticutThree sections of optic nerve were injured by crushing (the white diamond on the far left of each nerve marks the crush point.) The lower two nerves each

Updated on: January 11,2024

Researchers find that youthful proteins help nerves regrow

by Kim Krieger,University of ConnecticutThree sections of optic nerve were injured by crushing (the white diamond on the far left of each nerve marks the crush point.) The lower two nerves each

Updated on:January 11,2024

A somewhat systematic review of previous systematic reviews and meta-analyses about nutrition and Alzheimer's

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainA team from the International Education College of Zhejiang Chinese Medical University, Hangzhou, China, has conducted a review of s

Updated on: May 26,2024

A somewhat systematic review of previous systematic reviews and meta-analyses about nutrition and Alzheimer's

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainA team from the International Education College of Zhejiang Chinese Medical University, Hangzhou, China, has conducted a review of s

Updated on:May 26,2024

Using a neuromonitoring platform to improve care for traumatic brain injuries

by Tim Tedeschi,University of CincinnatiUC's neurocritical care team monitors metrics like blood flow, pressure, oxygen and glucose levels in the brain in real time and monitors trends and s

Updated on: January 10,2024

Using a neuromonitoring platform to improve care for traumatic brain injuries

by Tim Tedeschi,University of CincinnatiUC's neurocritical care team monitors metrics like blood flow, pressure, oxygen and glucose levels in the brain in real time and monitors trends and s

Updated on:January 10,2024

Unlikely that high cholesterol or statins increase the risk of dementia

by Cecilie Bakken Høstmark,University of OsloIn professor Kjetil Retterstøl's new study, he found that neither high cholesterol itself nor statins can explain an increased risk of developing

Updated on: June 04,2024

Unlikely that high cholesterol or statins increase the risk of dementia

by Cecilie Bakken Høstmark,University of OsloIn professor Kjetil Retterstøl's new study, he found that neither high cholesterol itself nor statins can explain an increased risk of developing

Updated on:June 04,2024

'Rhythm' or 'drift'—new tools can help better understand human attention

byUniversity of BirminghamCredit: CC0 Public DomainAccepted theories of how people's visual attention behaves in situations with lots of stimuli, such as crossing a busy street, may need to

Updated on: January 21,2024

'Rhythm' or 'drift'—new tools can help better understand human attention

byUniversity of BirminghamCredit: CC0 Public DomainAccepted theories of how people's visual attention behaves in situations with lots of stimuli, such as crossing a busy street, may need to

Updated on:January 21,2024

Researchers fully map neural connections of the fruit fly brain

byNational Institutes of Health50 largest neurons of the fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., Nature, 2024)A scientif

Updated on: October 18,2024

Researchers fully map neural connections of the fruit fly brain

byNational Institutes of Health50 largest neurons of the fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., Nature, 2024)A scientif

Updated on:October 18,2024

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on: April 06,2024

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on:April 06,2024

Emerging from a coma: Response to language can help assess states of consciousness

by Charlène Aubinet, Olivia Gosseries,The ConversationCredit: AI-generated imageA man—for the sake of this exercise, let's call him "Paul"—has a heart attack and his brain is starv

Updated on: February 18,2024

Emerging from a coma: Response to language can help assess states of consciousness

by Charlène Aubinet, Olivia Gosseries,The ConversationCredit: AI-generated imageA man—for the sake of this exercise, let's call him "Paul"—has a heart attack and his brain is starv

Updated on:February 18,2024

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on: June 04,2024

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on:June 04,2024

Researchers find about a quarter of mitochondrial disease patients suffer from malnutrition

byChildren's Hospital of PhiladelphiaA BMI classification. Most subjects had appropriate BMI; 3/22 (13.6%) adults and 12/38 (31.6%) children were underweight. B Patient-reported gastrointest

Updated on: December 28,2023

Researchers find about a quarter of mitochondrial disease patients suffer from malnutrition

byChildren's Hospital of PhiladelphiaA BMI classification. Most subjects had appropriate BMI; 3/22 (13.6%) adults and 12/38 (31.6%) children were underweight. B Patient-reported gastrointest

Updated on:December 28,2023

Study links long-term consumption of reused deep-fried oil with increased neurodegeneration

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainA new study found higher levels of neurodegeneration in rats that consumed reused deep-fried cooking oil

Updated on: March 28,2024

Study links long-term consumption of reused deep-fried oil with increased neurodegeneration

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainA new study found higher levels of neurodegeneration in rats that consumed reused deep-fried cooking oil

Updated on:March 28,2024