New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on: March 25,2024

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on:March 25,2024

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on: November 07,2024

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on:November 07,2024

Study reveals broader impact of Alzheimer's on brain function

by Stephen Fontenot,University of Texas at DallasAlzheimer's disease and aging are associated with distinct patterns of brain network disruption. Alzheimer's (left) exerts widespread imp

Updated on: January 10,2024

Study reveals broader impact of Alzheimer's on brain function

by Stephen Fontenot,University of Texas at DallasAlzheimer's disease and aging are associated with distinct patterns of brain network disruption. Alzheimer's (left) exerts widespread imp

Updated on:January 10,2024

A devastating nerve disease stalks a mountain village

Updated on: December 30,2024

A devastating nerve disease stalks a mountain village

Updated on:December 30,2024

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on: June 15,2024

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on:June 15,2024

Researchers develop shortcut to generate brain stem cells for age-related disease research

by The University of Hong KongCredit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad597A research team from the School of Biomedical Sciences, LKS Faculty of Medicine of the Unive

Updated on: March 19,2024

Researchers develop shortcut to generate brain stem cells for age-related disease research

by The University of Hong KongCredit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad597A research team from the School of Biomedical Sciences, LKS Faculty of Medicine of the Unive

Updated on:March 19,2024

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on: June 14,2024

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on:June 14,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on: November 29,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on:November 29,2024

Alzheimer's study delves into degraded brain connections

by University of Texas at DallasAs part of the study, researchers useddiffusion-tensor imaging to determine the integrity of white matter connections in the brain. Credit: University

Updated on: April 18,2024

Alzheimer's study delves into degraded brain connections

by University of Texas at DallasAs part of the study, researchers useddiffusion-tensor imaging to determine the integrity of white matter connections in the brain. Credit: University

Updated on:April 18,2024

Faster, stronger … smarter? New research shows the importance of brain training for junior athletes

by Kylie A Steel, Clare MacMahon and Todd Pickering,The ConversationCredit: CC0 Public Domain"Look for the gap!" "Move into space!" "Who's free?"Sound familiar?

Updated on: July 31,2024

Faster, stronger … smarter? New research shows the importance of brain training for junior athletes

by Kylie A Steel, Clare MacMahon and Todd Pickering,The ConversationCredit: CC0 Public Domain"Look for the gap!" "Move into space!" "Who's free?"Sound familiar?

Updated on:July 31,2024

Neuroimaging study reinforces theory of mental 'foraging,' inspiring new understanding of schizophrenia

byIndiana UniversitySchematic of an example fMRI run consisting of 1 category verbal fluency test, 1 control speaking condition, and 1 letter verbal fluency test. Black boxes illustrate examples

Updated on: January 11,2024

Neuroimaging study reinforces theory of mental 'foraging,' inspiring new understanding of schizophrenia

byIndiana UniversitySchematic of an example fMRI run consisting of 1 category verbal fluency test, 1 control speaking condition, and 1 letter verbal fluency test. Black boxes illustrate examples

Updated on:January 11,2024