Human stem cell models point to glia as key players in multiple sclerosis

byNew York Stem Cell FoundationGlia-enriched cultures from a primary progressive multiple sclerosis iPSC line showing astrocytes (yellow), oligodendrocytes (cyan), and neurons (magenta). Credit:

Updated on: September 11,2024

Human stem cell models point to glia as key players in multiple sclerosis

byNew York Stem Cell FoundationGlia-enriched cultures from a primary progressive multiple sclerosis iPSC line showing astrocytes (yellow), oligodendrocytes (cyan), and neurons (magenta). Credit:

Updated on:September 11,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on: April 02,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on:April 02,2024

Can computer use, crafts and games slow or prevent age-related memory loss?

by American Academy of NeurologyCredit: CC0 Public DomainA new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social acti

Updated on: May 22,2024

Can computer use, crafts and games slow or prevent age-related memory loss?

by American Academy of NeurologyCredit: CC0 Public DomainA new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social acti

Updated on:May 22,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on: February 21,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on:February 21,2024

New study identifies gene believed to be responsible for ALS and dementia

byCase Western Reserve UniversityRepresentative human spinal cord tissue imaged at 4X objective for DAPI (blue), CD80 (red), and Iba1 (green) from an C9ORF72 ALS case and a non-ALS control. Scal

Updated on: April 26,2024

New study identifies gene believed to be responsible for ALS and dementia

byCase Western Reserve UniversityRepresentative human spinal cord tissue imaged at 4X objective for DAPI (blue), CD80 (red), and Iba1 (green) from an C9ORF72 ALS case and a non-ALS control. Scal

Updated on:April 26,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on: April 27,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on:April 27,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on: January 11,2024

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on:January 11,2024

SuperAger brains resist protein tangles that lead to Alzheimer's

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainA new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region r

Updated on: May 05,2024

SuperAger brains resist protein tangles that lead to Alzheimer's

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainA new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region r

Updated on:May 05,2024

Physical therapy clinical trial demonstrates meaningful gains for stroke survivors

by Amy Cherry,University of DelawareStroke survivor Larry Christian (center) participates in high-intensity interval training in a clinical trial while research assistant Henry Wright (right) ob

Updated on: January 12,2024

Physical therapy clinical trial demonstrates meaningful gains for stroke survivors

by Amy Cherry,University of DelawareStroke survivor Larry Christian (center) participates in high-intensity interval training in a clinical trial while research assistant Henry Wright (right) ob

Updated on:January 12,2024

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on: February 05,2024

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on:February 05,2024