Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on: April 20,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on:April 20,2024

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on: April 06,2024

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on:April 06,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on: June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on:June 07,2024

Does the risk of stroke from common risk factors change as people age?

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainHigh blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decreas

Updated on: February 05,2024

Does the risk of stroke from common risk factors change as people age?

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainHigh blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decreas

Updated on:February 05,2024

More seniors may have undiagnosed dementia than previously thought

by University of MichiganCredit: CC0 Public DomainOnly 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medic

Updated on: June 05,2024

More seniors may have undiagnosed dementia than previously thought

by University of MichiganCredit: CC0 Public DomainOnly 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medic

Updated on:June 05,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on: April 08,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on:April 08,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on: January 10,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on:January 10,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on: February 03,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on:February 03,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on: January 12,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on:January 12,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on: April 28,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on:April 28,2024