Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on: January 12,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on:January 12,2024

New evidence for sub-network specializations within the default mode network of brain activation and self-perception

by Reichman University(A) Statistical parametric maps for movement of all body parts relative to rest condition following FDR correction. (B, C, D) Statistical parametric maps for face-movement relati

Updated on: February 21,2024

New evidence for sub-network specializations within the default mode network of brain activation and self-perception

by Reichman University(A) Statistical parametric maps for movement of all body parts relative to rest condition following FDR correction. (B, C, D) Statistical parametric maps for face-movement relati

Updated on:February 21,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on: June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on:June 07,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on: March 07,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on:March 07,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on: March 30,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on:March 30,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on: July 31,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on:July 31,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on: April 08,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on:April 08,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024