A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

Does shingles increase a person's risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainShingles, a viral infection caused by the reactivation of the chickenpox virus, results in a painful blistering rash along one side of the

Updated on: May 20,2024

Does shingles increase a person's risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainShingles, a viral infection caused by the reactivation of the chickenpox virus, results in a painful blistering rash along one side of the

Updated on:May 20,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on: February 21,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on:February 21,2024

Brain damage study reveals part of the brain necessary for helping others

byUniversity of BirminghamCredit: CC0 Public DomainOur willingness to help others is governed by a specific brain region pinpointed by researchers in a study of patients with brain damage to tha

Updated on: May 30,2024

Brain damage study reveals part of the brain necessary for helping others

byUniversity of BirminghamCredit: CC0 Public DomainOur willingness to help others is governed by a specific brain region pinpointed by researchers in a study of patients with brain damage to tha

Updated on:May 30,2024

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on: June 04,2024

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on:June 04,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on: April 23,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on:April 23,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on: March 19,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on:March 19,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on: January 11,2024

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on:January 11,2024