New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on: April 25,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on:April 25,2024

Untangling the brain: New research offers hope for Alzheimer's disease

by Arizona State UniversityThe development of neurodegenerative pathology resulting from low levels of the protein Rbbp7 (on the left), compared with normal levels associated with a healthy brain

Updated on: July 01,2024

Untangling the brain: New research offers hope for Alzheimer's disease

by Arizona State UniversityThe development of neurodegenerative pathology resulting from low levels of the protein Rbbp7 (on the left), compared with normal levels associated with a healthy brain

Updated on:July 01,2024

Physical activity level inversely linked to Parkinson's disease in women

by Elana GotkineIn women, a higher physical activity (PA) level is associated with a lower incidence of Parkinson's disease (PD), according to a study published online May 17 inNeurology.Ber

Updated on: May 16,2024

Physical activity level inversely linked to Parkinson's disease in women

by Elana GotkineIn women, a higher physical activity (PA) level is associated with a lower incidence of Parkinson's disease (PD), according to a study published online May 17 inNeurology.Ber

Updated on:May 16,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on: December 18,2024

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on:December 18,2024

How the brain processes numbers: New procedure improves measurement of human brain activity

by Technical University MunichProf. Simon Jacob (left) and his team have developed a new approach to learning the basics about how our brains work. During awake surgery, tumor patients support th

Updated on: February 21,2024

How the brain processes numbers: New procedure improves measurement of human brain activity

by Technical University MunichProf. Simon Jacob (left) and his team have developed a new approach to learning the basics about how our brains work. During awake surgery, tumor patients support th

Updated on:February 21,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Higher education and language skills may help ward off dementia

by University of WaterlooCredit: Pixabay/CC0 Public DomainNew research has found that people with mild cognitive impairment may not inevitably develop dementia and, in fact, having higher educati

Updated on: June 04,2024

Higher education and language skills may help ward off dementia

by University of WaterlooCredit: Pixabay/CC0 Public DomainNew research has found that people with mild cognitive impairment may not inevitably develop dementia and, in fact, having higher educati

Updated on:June 04,2024